Evidence map›Paper›PMID 38939899›Full record

ArticleJournal of extracellular biology2024

RAB31 drives extracellular vesicle fusion and cancer-associated fibroblast formation leading to oxaliplatin resistance in colorectal cancer.

Yu-Chan Chang, Yi-Fang Yang, Chien-Hsiu Li, Ming-Hsien Chan, Meng-Lun Lu, Ming-Huang Chen, Chi-Long Chen, Michael Hsiao

Abstract read
In one paragraph

Article in Journal of extracellular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. EMT and cancer: what clinicians should know.Nature reviews. Clinical oncology · 2025
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yu-Chan ChangDepartment of Biomedical Imaging and Radiological Sciences National Yang Ming Chiao Tung University Taipei Taiwan.
Yi-Fang YangDepartment of Medical Education and Research Kaohsiung Veterans General Hospital Kaohsiung Taiwan.
Chien-Hsiu LiGenomics Research Center Academia Sinica Taipei Taiwan.
Ming-Hsien ChanDepartment of Biomedical Imaging and Radiological Sciences National Yang Ming Chiao Tung University Taipei Taiwan.
Meng-Lun LuDepartment of Oncology Taipei Veterans General Hospital Taipei Taiwan.
Ming-Huang ChenDepartment of Oncology Taipei Veterans General Hospital Taipei Taiwan.
Chi-Long ChenDepartment of Pathology Taipei Medical University Hospital, Taipei Medical University Taipei Taiwan.
Michael HsiaoGenomics Research Center Academia Sinica Taipei Taiwan.ORCID https://orcid.org/0000-0001-8529-9213

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelial-mesenchymal transition (EMT) is associated with tumorigenesis and drug resistance. The Rab superfamily of small G-proteins plays a role in regulating cell cytoskeleton and vesicle transport. However, it is not yet clear how the Rab family contributes to cancer progression by participating in EMT. By analysing various in silico datasets, we identified a statistically significant increase in

Indexed as

AGR2colon cancerepithelial‐mesenchymal transitionoxaliplatin resistanceRAB31

Identifiers

PMID38939899
PMCPMC11080812

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.