Evidence map›Paper›PMID 38939861›Full record

ReviewExploration (Beijing, China)2024

Advances in the treatment of atherosclerosis with ligand-modified nanocarriers.

Xiujiao Deng, Jinghao Wang, Shanshan Yu, Suiyi Tan, Tingting Yu, Qiaxin Xu, Nenghua Chen, Siqi Zhang, Ming-Rong Zhang, Kuan Hu and 1 more

Abstract readReview
In one paragraph

Review in Exploration (Beijing, China), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Glycyrrhizic Acid Alleviates Atherosclerosis inInternational journal of molecular sciences · 2026
    Article
  5. Review
  6. Pro-ATO/Allicin Liposomes for Dual-Pathway Targeting of p53-Mutant Tumors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Targeted drug delivery systems for atherosclerosis.Journal of nanobiotechnology · 2025
    Review
  18. Article
  19. Review
  20. Recent Advances in Nanozymes for the Treatment of Atherosclerosis.International journal of nanomedicine · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiujiao DengDepartment of Pharmacy The First Affiliated Hospital of Jinan University Guangzhou China.
Jinghao WangDepartment of Pharmacy The First Affiliated Hospital of Jinan University Guangzhou China.
Shanshan YuDepartment of Pharmacy Zhujiang Hospital Southern Medical University Guangzhou China.
Suiyi TanProvincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences Southern Medical University Guangzhou China.
Tingting YuDepartment of Pharmacy The First Affiliated Hospital of Jinan University Guangzhou China.
Qiaxin XuDepartment of Pharmacy The First Affiliated Hospital of Jinan University Guangzhou China.
Nenghua ChenDepartment of Pharmacy The First Affiliated Hospital of Jinan University Guangzhou China.
Siqi ZhangState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Ming-Rong ZhangDepartment of Advanced Nuclear Medicine Sciences, Institute of Quantum Medical, Science National Institutes for Quantum Science and Technology Chiba Japan.
Kuan HuState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.ORCID https://orcid.org/0000-0003-2448-2254
Zeyu XiaoThe Guangzhou Key Laboratory of Basic and Translational Research on Chronic Diseases Jinan University Guangzhou China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis, a chronic disease associated with metabolism, poses a significant risk to human well-being. Currently, existing treatments for atherosclerosis lack sufficient efficiency, while the utilization of surface-modified nanoparticles holds the potential to deliver highly effective therapeutic outcomes. These nanoparticles can target and bind to specific receptors that are abnormally over-expressed in atherosclerotic conditions. This paper reviews recent research (2018-present) advances in various ligand-modified nanoparticle systems targeting atherosclerosis by specifically targeting signature molecules in the hope of precise treatment at the molecular level and concludes with a discussion of the challenges and prospects in this field. The intention of this review is to inspire novel concepts for the design and advancement of targeted nanomedicines tailored specifically for the treatment of atherosclerosis.

Indexed as

atherosclerosisdrug deliveryligand‐modifiednano‐drugstargeted therapies

Identifiers

PMID38939861
PMCPMC11189587

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.