Evidence map›Paper›PMID 38939836›Full record

ReviewFrontiers in pharmacology2024

Critical roles of lncRNA-mediated autophagy in urologic malignancies.

Lifeng Gan, Liying Zheng, Junrong Zou, Peiyue Luo, Tao Chen, Jun Zou, Wei Li, Qi Chen, Le Cheng, Fangtao Zhang and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lifeng GanThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Liying ZhengDepartment of Graduate, The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.
Junrong ZouDepartment of Urology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.
Peiyue LuoThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Tao ChenThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Jun ZouThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Wei LiThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Qi ChenThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Le ChengThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Fangtao ZhangThe First Clinical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Biao QianDepartment of Urology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urologic oncology is a significant public health concern on a global scale. Recent research indicates that long chain non-coding RNAs (lncRNAs) and autophagy play crucial roles in various cancers, including urologic malignancies. This article provides a summary of the latest research findings, suggesting that lncRNA-mediated autophagy could either suppress or promote tumors in prostate, kidney, and bladder cancers. The intricate network involving different lncRNAs, target genes, and mediated signaling pathways plays a crucial role in urological malignancies by modulating the autophagic process. Dysregulated expression of lncRNAs can disrupt autophagy, leading to tumorigenesis, progression, and enhanced resistance to therapy. Consequently, targeting particular lncRNAs that control autophagy could serve as a dependable diagnostic tool and a promising prognostic biomarker in urologic oncology, while also holding potential as an effective therapeutic approach.

Indexed as

autophagylncRNAmolecular mechanismspathwaysurologic oncologies

Identifiers

PMID38939836
PMCPMC11208713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.