Evidence map›Paper›PMID 38939719›Full record

ReviewJACC. Advances2022

Advances in the Staging and Phenotyping of Cardiogenic Shock: Part 1 of 2.

Jacob C Jentzer, Corbin Rayfield, Sabri Soussi, David D Berg, Jason N Kennedy, Shashank S Sinha, David A Baran, Emily Brant, Alexandre Mebazaa, Filio Billia and 3 more

Abstract readReview
In one paragraph

Review in JACC. Advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Why Molecular Subphenotyping Is Needed in Cardiogenic Shock and How to Accomplish This.American journal of respiratory and critical care medicine · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Targeted proteomic profiling of cardiogenic shock in the cardiac intensive care unit.European heart journal. Acute cardiovascular care · 2024
    Article
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jacob C JentzerDepartment of Cardiovascular Medicine, Mayo Clinic Rochester, Rochester, Minnesota, USA.
Corbin RayfieldDepartment of Cardiovascular Medicine, Mayo Clinic Arizona, Scottsdale, Arizona, USA.
Sabri SoussiDepartment of Anesthesiology and Critical Care, Lariboisière-Saint-Louis Hospitals, DMU Parabol, AP-HP Nord, Inserm UMR-S 942, Cardiovascular Markers in Stress Conditions (MASCOT), University of Paris, Paris, France.
David D BergTIMI Study Group, Department of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Jason N KennedyDepartment of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Shashank S SinhaINOVA Heart and Vascular Institute, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
David A BaranCleveland Clinic Heart Vascular and Thoracic Institute, Weston, Florida, USA.
Emily BrantDepartment of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Alexandre MebazaaDepartment of Anesthesiology and Critical Care, Lariboisière-Saint-Louis Hospitals, DMU Parabol, AP-HP Nord, Inserm UMR-S 942, Cardiovascular Markers in Stress Conditions (MASCOT), University of Paris, Paris, France.
Filio BilliaPeter Munk Cardiac Center and Ted Roger's Center for Heart Research, Toronto, Ontario, Canada.
Navin K KapurThe Cardiovascular Center, Tufts Medical Center, Boston, Massachusetts, USA.
Timothy D HenryThe Carl and Edyth Lindner Center for Research and Education at the Christ Hospital Health Network, Cincinnati, Ohio, USA.
Patrick R LawlerPeter Munk Cardiac Center and Ted Roger's Center for Heart Research, Toronto, Ontario, Canada.

Funding

Sepsis subtypes: biology, treatment, and bedside applicationR35GM119519 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Christopher W. Seymour · 2016 to 2026
$4.9M
REMISE study: REMnant biospecimen Investigation in SEpsisR21GM144851 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SEYMOUR, CHRISTOPHER WARREN · 2022 to 2023
$438k
NIGMS NIH HHS R21 GM144851NIGMS NIH HHS R35 GM119519
6 · The paper itself

Abstract

Cardiogenic shock (CS) is a heterogeneous syndrome reflecting a broad spectrum of shock severity, diverse etiologies, variable cardiac function, different hemodynamic trajectories, and concomitant organ dysfunction. These factors influence the clinical presentation, management, response to therapy, and outcomes of CS patients, necessitating a tailored approach to care. To better understand the variability inherent to CS populations, recent algorithms for staging the severity of CS have been described and validated. This paper is part 1 of a 2-part state-of-the-art review. In this first article, we consider the context for clinical staging and stratification in CS with a focus on established severity staging systems for CS and their use for risk stratification and clinical care. We describe the use of staging for predicting outcomes in populations with or at risk for CS, including risk modifiers that provide more nuanced risk stratification, and highlight how these approaches may allow individualized care.

Indexed as

cardiac intensive care unitcardiogenic shockmortalityphenotypesshock

Identifiers

PMID38939719
PMCPMC11198663

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.