ArticleJACC. Advances2024
Cardiovascular Outcomes in Fontan Patients With Right vs Left Univentricular Morphology: A Multicenter Study.
Article in JACC. Advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Long-Term Fate of the Systemic Right Ventricle: In Patients with Bi-ventricle Versus Single Ventricle.Pediatric cardiology · 2026Article
- Contemporary Management and Future Directions of Adults Living With a Fontan Circulation.JACC. Advances · 2026Review
- Predictors of Higher Peak Exercise Oxygen Uptake in a Cohort of Adult Patients with Fontan Circulation.Journal of clinical medicine · 2026Article
- Outcome of Fontan Patients After Reaching Adolescence: The Impact of Hypoplastic Left Heart Syndrome.Journal of clinical medicine · 2025Article
- Respiratory Function of Fontan Pediatric Patients with Hypoplastic Left Heart Syndrome and Other Morphologies of Functionally Single Ventricle-A Pilot Study.Children (Basel, Switzerland) · 2025Article
- Impact of cardiovascular magnetic resonance in single ventricle physiology: a narrative review.Cardiovascular diagnosis and therapy · 2024Review
- Cardiovascular Outcomes Associated With Hypoplastic Left Heart Syndrome Versus Other Types of Single Right Ventricle: A Multicenter Study.Journal of the American Heart Association · 2024Article
- The impact of donor-recipient age difference on graft survival after heart transplant in adults with congenital heart disease.JHLT open · 2024Article
- Risk Factors for Adverse Events in the Fontan Population: Does Ventricular Morphology Play a Role?JACC. Advances · 2024Article
Corrections and comments
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Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: There is a paucity of data on long-term outcomes after Fontan palliation in patients with a dominant morphological univentricular right (uRV) vs left (uLV) ventricle. Objectives: The purpose of this study was to compare the incidence of atrial arrhythmias, thromboembolic events, cardiac transplantation, and death following Fontan palliation in patients with uRV vs uLV. Methods: The Alliance for Adult Research in Congenital Cardiology conducted a multicenter retrospective cohort study on patients with total cavopulmonary connection Fontan palliation across 12 centers in North America. All components of the composite outcome, that is, atrial arrhythmias, thromboembolic events, cardiac transplantation, and death, were reviewed and classified by a blinded adjudicating committee. Time-to-event analyses were performed that accounted for competing risks. Results: A total of 384 patients were followed for 10.5 ± 5.9 years. The composite outcome occurred in 3.7 vs 1.7 cases per 100 person-years for uRV (N = 171) vs uLV (N = 213), respectively ( Conclusions: Fontan patients with uRV vs uLV morphology have a higher incidence of adverse cardiovascular events, including atrial arrhythmia, cardiac transplantation, and all-cause mortality.
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