Evidence map›Paper›PMID 38939629›Full record

ArticleJACC. Advances2024

Impact of an Organized Treatment Pathway on Management of Atrial Fibrillation: The ER2EP Study.

Dhanunjaya Lakkireddy, Adnan Ahmed, Danish Bawa, Jalaj Garg, Donita Atkins, Rajesh Kabra, Nicholas Pham, Jacelyn Bernholtz, Douglas Darden, Sudha Bommana and 10 more

Registry-linked trialAbstract read
In one paragraph

Article in JACC. Advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04476524 (Clinical and Economic Impact of an Organized Treatment Pathway on Atrial Fibrillation Patient Management From the Emergency Room), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04476524 unknown statusnot on this map

Clinical and Economic Impact of an Organized Treatment Pathway on Atrial Fibrillation Patient Management From the Emergency Room

TypeobservationalSponsorKansas City Heart Rhythm Research FoundationRan2020 to 2021Enrolled200ConditionsCardiac Arrhythmia, Atrial FibrillationArmsQuality improvement
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Dhanunjaya LakkireddyCardiac Arrhythmia Service, Kansas City Heart Rhythm Institute, Overland Park, Kansas, USA.
Adnan AhmedCardiac Arrhythmia Service, Kansas City Heart Rhythm Institute, Overland Park, Kansas, USA.
Danish BawaCardiac Arrhythmia Service, Kansas City Heart Rhythm Institute, Overland Park, Kansas, USA.
Jalaj GargCardiac Arrhythmia Service, Loma Linda University Hospital, Loma Linda, California, USA.
Donita AtkinsCardiac Arrhythmia Service, Kansas City Heart Rhythm Institute, Overland Park, Kansas, USA.
Rajesh KabraCardiac Arrhythmia Service, Kansas City Heart Rhythm Institute, Overland Park, Kansas, USA.
Nicholas PhamCardiac Arrhythmia Service, Kansas City Heart Rhythm Institute, Overland Park, Kansas, USA.
Jacelyn BernholtzCardiac Arrhythmia Service, Kansas City Heart Rhythm Institute, Overland Park, Kansas, USA.
Douglas DardenCardiac Arrhythmia Service, Kansas City Heart Rhythm Institute, Overland Park, Kansas, USA.
Sudha BommanaCardiac Arrhythmia Service, Kansas City Heart Rhythm Institute, Overland Park, Kansas, USA.
Rakesh GopinathannairCardiac Arrhythmia Service, Kansas City Heart Rhythm Institute, Overland Park, Kansas, USA.
Naga Venkata K PothineniCardiac Arrhythmia Service, Kansas City Heart Rhythm Institute, Overland Park, Kansas, USA.
Peter ParkCardiac Arrhythmia Service, Kansas City Heart Rhythm Institute, Overland Park, Kansas, USA.
Chandra VasamreddyCardiac Arrhythmia Service, Kansas City Heart Rhythm Institute, Overland Park, Kansas, USA.
Rangarao TummalaCardiac Arrhythmia Service, Kansas City Heart Rhythm Institute, Overland Park, Kansas, USA.
Scott KoerberCardiac Arrhythmia Service, Kansas City Heart Rhythm Institute, Overland Park, Kansas, USA.
Domenico Della RoccaCardiac Arrhythmia Service, Texas Cardiac Arrhythmia Institute, Austin, Texas, USA.
Luigi DiBiaseDivision of Cardiology, Cardiac Arrhythmia Service, Albert Einstein/Montefiore Medical Center, Bronx, New York, USA.
Amin Al-AhmadCardiac Arrhythmia Service, Texas Cardiac Arrhythmia Institute, Austin, Texas, USA.
Andrea NataleCardiac Arrhythmia Service, Texas Cardiac Arrhythmia Institute, Austin, Texas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atrial fibrillation (AF) is the most common arrhythmia reported worldwide. There is significant heterogeneity in AF care pathways for a patient seen in the emergency room, impacting access to guideline-driven therapies. Objectives: The purpose of this study was to compare the difference in AF outcomes between those treated with an organized treatment pathway vs routine-care approach. Methods: The emergency room to electrophysiology service study (ER2EP) is a multicenter, prospective observational registry (NCT04476524) enrolling patients with AF from sites where a pathway for management of AF was put in place compared to sites where a pathway was not in place within the same health system and the same physicians providing services at all sites. Multivariable regression modeling was performed to identify predictors of clinical outcomes. Beta coefficient or odds ratio was reported as appropriate. Results: A total of 500 patients (ER2EP group, n = 250; control group, n = 250) were included in the study. The mean age was 73.4 ± 12.9 years, and 52.2% were males. There was a statistically significant difference in primary endpoint [time to ablation (56 ± 50.9 days vs 183.3 ± 109.5 days; Conclusions: This study provides evidence that having an organized pathway from the emergency department for AF patients involving electrophysiology services can improve early access to definitive therapies and clinical outcomes.

Indexed as

antiarrhythmic drugsatrial fibrillationelectrophysiology serviceemergency roomhospitalizationlength of stayoral anticoagulationorganized treatment pathwayradiofrequency ablationstroke

Identifiers

PMID38939629
PMCPMC11198052

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.