Evidence map›Paper›PMID 38939594›Full record

ArticleJACC. Advances2023

Treatment Intensity for the Management of Cardiogenic Shock: Comparison Between STEMI and Non-STEMI.

Shashank S Sinha, Mohit Pahuja, Rachna Kataria, Vanessa Blumer, Jaime Hernandez-Montfort, Manreet Kanwar, A Reshad Garan, Yijing Zhang, Jeffrey A Marbach, Adnan Khalif and 25 more

Abstract read
In one paragraph

Article in JACC. Advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Profiling of Cardiogenic Shock: Incorporating Machine Learning Into Bedside Management.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Shashank S SinhaInova Heart and Vascular Institute, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Mohit PahujaUniversity of Oklahoma Health Science Center, Oklahoma City, Oklahoma, USA.
Rachna KatariaBrown University, Lifespan Cardiovascular Center, Providence, Rhode Island, USA.
Vanessa BlumerDepartment of Cardiovascular Medicine, Heart and Vascular Institute, Kaufman Center for Heart Failure, Cleveland Clinic, Cleveland, Ohio, USA.
Jaime Hernandez-MontfortAdvanced Heart Disease Program, Baylor Scott & White Health, Temple, Texas, USA.
Manreet KanwarCardiovascular Institute at Allegheny Health Network, Pittsburgh, Pennsylvania, USA.
A Reshad GaranBeth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Yijing ZhangThe CardioVascular Center, Tufts Medical Center, Boston, Massachusetts, USA.
Jeffrey A MarbachBeth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Adnan KhalifCardiovascular Institute at Allegheny Health Network, Pittsburgh, Pennsylvania, USA.
Saraschandra VallabhajosyulaWake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
Sandeep NathanUniversity of Chicago Medicine, Chicago, Illinois, USA.
Jacob AbrahamProvidence Heart Institute, Center for Cardiovascular Analytics, Research, and Data Science (CARDS), Providence St. Joseph Health, Portland, Oregon, USA.
Borui LiThe CardioVascular Center, Tufts Medical Center, Boston, Massachusetts, USA.
Katherine L ThayerThe CardioVascular Center, Tufts Medical Center, Boston, Massachusetts, USA.
Paulina BacaThe CardioVascular Center, Tufts Medical Center, Boston, Massachusetts, USA.
Fatou DiengThe CardioVascular Center, Tufts Medical Center, Boston, Massachusetts, USA.
Neil M HarwaniThe CardioVascular Center, Tufts Medical Center, Boston, Massachusetts, USA.
Michael Y YinThe CardioVascular Center, Tufts Medical Center, Boston, Massachusetts, USA.
Anthony J FaugnoThe CardioVascular Center, Tufts Medical Center, Boston, Massachusetts, USA.
Haroon A FarazHackensack Meridian Health, Hackensack, New Jersey, USA.
Maya GuglinIndiana University Health Advanced Heart and Lung Care, Indianapolis, Indiana, USA.
Gavin W HickeyUniversity of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Detlef WenckerAdvanced Heart Disease Program, Baylor Scott & White Health, Temple, Texas, USA.
Shelley HallBaylor Scott & White Advanced Heart Failure Clinic, Dallas, Texas, USA.
Andrew D SchwartzmanMaine Medical Center, Portland, Maine, USA.
Wissam KhalifeUniversity of Texas Medical Branch, Galveston, Texas, USA.
Song LiUniversity of Washington Medical Center, Seattle, Washington, USA.
Claudius MahrUniversity of Washington Medical Center, Seattle, Washington, USA.
Ju H KimHouston Methodist Research Institute, Houston, Texas, USA.
Arvind BhimarajHouston Methodist Research Institute, Houston, Texas, USA.
Van-Khue TonMassachusetts General Hospital, Boston, MA, USA.
Esther VorovichNorthwestern Medicine, Chicago, Illinois, USA.
Daniel BurkhoffCardiovascular Research Foundation, New York, New York, USA.
Navin K KapurThe CardioVascular Center, Tufts Medical Center, Boston, Massachusetts, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiogenic shock is a leading cause of mortality in patients with acute myocardial infarction. Objectives: The authors sought to compare clinical characteristics, hospital trajectory, and drug and device use between patients with ST-segment elevation myocardial infarction-related cardiogenic shock (STEMI-CS) and those without (non-ST-segment elevation myocardial infarction complicated by cardiogenic shock [NSTEMI-CS]). Methods: We analyzed data from 1,110 adult admissions with cardiogenic shock complicating acute myocardial infarction (AMI-CS) across 17 centers within Cardiogenic Shock Working Group. The primary end point was in-hospital mortality. Results: Our study included 1,110 patients with AMI-CS, of which 731 (65.8%) had STEMI-CS and 379 (34.2%) had NSTEMI-CS. Most patients were male (STEMI-CS: 71.6%, NSTEMI-CS: 66.5%) and White (STEMI-CS: 53.8%, NSTEMI-CS: 64.1%). In-hospital mortality was 41% and was similar among patients with STEMI-CS and NSTEMI-CS (43% vs 39%, Conclusions: Despite increasing use of inotropic and vasoactive support and mechanical circulatory support throughout the hospitalization, both patients with STEMI-CS and NSTEMI-CS remain at increased risk for in-hospital mortality. Randomized controls trials are needed to elucidate whether timing and sequence of escalation of support improves outcomes in patients with AMI-CS.

Indexed as

acute myocardial infarctioncardiogenic shockheart failure

Identifiers

PMID38939594
PMCPMC11198573

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.