ArticleJACC. Advances2023
Sex Differences in Heart Failure Following Acute Coronary Syndromes.
Article in JACC. Advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04008173 (The International Survey of Acute Coronary Syndromes-ARCHIVES), which is not on this map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The International Survey of Acute Coronary Syndromes-ARCHIVES
Who cites it
14 citing papers in PubMed.
- Sex differences in risk factor control and medication adherence post-ACS: insights from the TEXTMEDS randomised clinical trial.Open heart · 2026Trial
- Prevention of acute myocardial infarction induced heart failure by intracoronary infusion of mesenchymal stem cells: phase 3 randomised clinical trial (PREVENT-TAHA8).BMJ (Clinical research ed.) · 2025Trial
- Ageing, women's health and personalised medicine: Advancing artificial intelligence and therapeutics through the blueprint theory paradigm.Experimental physiology · 2026Article
- Sex disparities in STEMI care: pre-hospital delay and acute heart failure.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026Article
- Response to 'Prospective comparison of temporal changes in myocardial function in women with Takotsubo versus anterior STEMI'.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Article
- Mandatory First-Aid Training in the Workplace: An Epidemiological Assessment of the Use of Acetylsalicylic Acid Therapy.Epidemiologia (Basel, Switzerland) · 2025Article
- Changing clinical perspectives on sex and healthcare disparities in ischaemic heart disease.The Lancet regional health. Europe · 2025Review
- Coronary microvascular dysfunction and its role in heart failure with preserved ejection fraction for future prevention and treatment.American journal of preventive cardiology · 2025Article
- Age and sex differences in the efficacy of early invasive strategy for non-ST-elevation acute coronary syndrome: A comparative analysis in stable patients.American journal of preventive cardiology · 2025Article
- Long-term gender disparities in new-onset heart failure after acute coronary syndrome.ESC heart failure · 2024Article
- Acute Coronary Syndrome in Elderly Patients: How to Tackle Them?Journal of clinical medicine · 2024Review
- Profile and Prognostic Impact of Multimorbidity in Elderly Patients with Heart Failure: Are there Differences between Men and Women?Current heart failure reports · 2024Review
- Heart Failure After Acute Coronary Syndrome: A Comprehensive Analysis from Bosnia and Herzegovina.Materia socio-medica · 2024Article
- Female Sex and Acute Heart Failure Predict Mortality Following Acute Coronary Syndrome.JACC. Advances · 2023Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: There have been conflicting reports regarding outcomes in women presenting with an acute coronary syndrome (ACS). Objectives: The objective of the study was to examine sex-specific differences in 30-day mortality in patients with ACS and acute heart failure (HF) at the time of presentation. Methods: This was a retrospective study of patients included in the International Survey of Acute Coronary Syndromes-ARCHIVES (ISACS-ARCHIVES; NCT04008173). Acute HF was defined as Killip classes ≥2. Participants were stratified according to ACS presentation: ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation ACS (NSTE-ACS). Differences in 30-day mortality and acute HF presentation at admission between sexes were examined using inverse propensity weighting based on the propensity score. Estimates were compared by test of interaction on the log scale. Results: A total of 87,812 patients were included, of whom 30,922 (35.2%) were women. Mortality was higher in women compared with men in those presenting with STEMI (risk ratio [RR]: 1.65; 95% CI: 1.56-1.73) and NSTE-ACS (RR: 1.18; 95% CI: 1.09-1.28; Conclusions: In patients presenting with ACS, mortality is higher in women. The presence of acute HF at hospital presentation increases the risk of mortality in both sexes. Women with STEMI are more likely to present with acute HF and this may, in part, explain sex differences in mortality. These findings may be helpful to improve sex-specific personalized risk stratification.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.