ReviewJournal of conservative dentistry and endodontics2024
Pulp regeneration treatment using different bioactive materials in permanent teeth of pediatric subjects.
Review in Journal of conservative dentistry and endodontics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Efficacy of White Mineral Trioxide Aggregate in Regenerative Endodontic Procedures and Apexification for Immature Permanent Teeth: A Systematic Review and Meta-Analysis.International dental journal · 2026Pooled it
- Evaluation of the Accuracy of Electronic Apex Locators in Modern Endodontics: An Umbrella Review.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Oral Health-Related Quality of Life in Pediatric Subjects with Molar Incisor Hypomineralization: An Umbrella Review of Domain-Specific Impact and Treatment-Related Changes.Children (Basel, Switzerland) · 2026Review
- Predictors of Dental Needle Bevel Deformation: Gauge, Insertion Frequency, and Length as Key Determinants.Dentistry journal · 2026Article
- Evaluation of cytotoxicity, setting time, and mineralization potential of mineral trioxide aggregate withJournal of conservative dentistry and endodontics · 2026Article
- Biocompatibility of carbazochrome sodium sulfonate on human dental pulp stem cells: AnJournal of conservative dentistry and endodontics · 2026Article
- Article
- An Integrated Care Pathway for Pediatric Oral Health: Baseline Multicenter Analysis of Dental Caries, Malocclusions, and Oral Hygiene in Three Italian Regions.Children (Basel, Switzerland) · 2026Article
- Collagen Scaffolds in Regenerative Endodontic Procedures: Current Evidence, Limitations, and Future Perspectives.Polymers · 2026Review
- Single-Agent Sedation for Behavioral Management in Pediatric Dentistry: An Umbrella Review of Agents, Routes of Administration, Providers, and Clinical Settings.Children (Basel, Switzerland) · 2026Review
- Regenerative Strategies in Pediatric Dentistry: A Comprehensive Overview of Tissue Engineering from Past to Future.Advances in experimental medicine and biology · 2026Review
- Effect of guided tissue regeneration on the outcome of surgical endodontic treatment: An umbrella review.Journal of conservative dentistry and endodontics · 2025Review
- Advanced Platelet-Rich Fibrin Plus Sealed Exclusively with Glass Ionomer Cement: Setting a New Standard for Healing, Aesthetics and Predictive Modelling in Regenerative Endodontics.Materials (Basel, Switzerland) · 2025Article
- Bioactive Materials in Pediatric Endodontics: Current Applications and Future Directions.Cureus · 2025Review
- The Diagnostic Accuracy of Pulse Oximetry for Assessing Pulp Vitality: A Systematic Review.Cureus · 2025Review
- Root development of immature necrotic permanent teeth following regenerative endodontic process: Case series.Dental research journal · 2025Article
- Activation of Irrigants in Root Canals with Open Apices: A Narrative Review.Journal of clinical medicine · 2024Review
- Clinical efficacy of platelet-rich fibrin, injectable platelet-rich fibrin, and advanced platelet-rich fibrin in regenerative endodontics: A case series.Journal of conservative dentistry and endodontics · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Objectives: The present systematic review aims to assess the success rate of the pulp regeneration treatment, according to the American Association of Endodontists (AAE) criteria, using different bioactive materials in permanent teeth of pediatric subjects (6-17 years of age). Materials and Methods: The study protocol was registered on PROSPERO and adhered to the Preferred Reporting Items for Systematic Reviews and Meta-analyses statement. The question formulation was accomplished using the PICO model, and an electronic search was carried out on Scopus, MEDLINE/PubMed, Web of Science, and Cochrane databases till April 1, 2023. A total of 30 studies were established to fulfill the inclusion criteria of this systematic review. Results: A total of 273 teeth have been treated with pulp regeneration treatment. By comparing different biomaterials and the success criteria defined by the AAE, the material associated with a higher success rate was found to be the white mineral trioxide aggregate. However, the overall success rate of pulp regeneration treatment was reported for 248 out of 273 teeth (91.20%). Conclusions: Data obtained support the potential that regenerative endodontics aids in continuing root development in permanent immature teeth. Further studies are needed for a more extensive evaluation of the use of different biomaterials and the success rate in regenerative endodontics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.