Evidence map›Paper›PMID 38939426›Full record

ArticleActa medica Philippina2024

Molecular Biomarkers Detected Using Fluorescence in situ Hybridization in a Filipino with Retinoblastoma.

Arnold Dominic A Barzaga, Glenmarie Angelica S Perias, Lia Angela E Reyes, Patrick Gabriel G Moreno, Patrick R Relacion, Richelle Ann M Manalo, Yasmyne C Ronquillo, Francisco M Heralde

Abstract read
In one paragraph

Article in Acta medica Philippina, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Arnold Dominic A BarzagaDepartment of Biochemistry and Molecular Biology, College of Medicine, University of the Philippines Manila.
Glenmarie Angelica S PeriasDepartment of Biochemistry and Molecular Biology, College of Medicine, University of the Philippines Manila.
Lia Angela E ReyesDepartment of Biochemistry and Molecular Biology, College of Medicine, University of the Philippines Manila.
Patrick Gabriel G MorenoDepartment of Biochemistry and Molecular Biology, College of Medicine, University of the Philippines Manila.
Patrick R RelacionDepartment of Biochemistry and Molecular Biology, College of Medicine, University of the Philippines Manila.
Richelle Ann M ManaloNational Institute of Health, University of the Philippines Manila.
Yasmyne C RonquilloHoopes Durrie Rivera Research.
Francisco M HeraldeDepartment of Biochemistry and Molecular Biology, College of Medicine, University of the Philippines Manila.

Funding

Mechanisms and specificity of sodium channel trafficking: Developing a novel analgesic strategyF31NS122417 · NINDS · YALE UNIVERSITY · PI HIGERD, GRANT PHILIP · 2021 to 2022
$62k
NINDS NIH HHS F31 NS122417
6 · The paper itself

Abstract

Background and Objective: Retinoblastoma is one of the most common intraocular cancers among children usually caused by the loss of retinoblastoma protein function. Despite being a highly heritable disease, conventional diagnostic and prognostic methods depend on clinical examination, with limited consideration of cancer genetics in the standard of care. Methods: Hematoxylin & Eosin (H&E) staining was utilized to characterize the retinoblastoma tissue while fluorescence in situ hybridization (FISH) using probes specific to Results: The H&E staining in the retinoblastoma tissue shows poorly differentiated cells with prominent basophilic nuclei. Conclusion: These findings suggest that

Indexed as

biomarkersCD133hybridization in situretinoblastoma

Identifiers

PMID38939426
PMCPMC11199350

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.