Evidence map›Paper›PMID 38939391›Full record

ReviewJACC. Advances2024

Environmental Pollution and Cardiovascular Disease: Part 1 of 2: Air Pollution.

Usman Sagheer, Sadeer Al-Kindi, Shady Abohashem, Colin T Phillips, Jamal S Rana, Aruni Bhatnagar, Martha Gulati, Sanjay Rajagopalan, Dinesh K Kalra

Abstract readReview
In one paragraph

Review in JACC. Advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Modeling the Exposome in Murine Cardiovascular Disease.JACC. Basic to translational science · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Usman SagheerDivision of Cardiology, Department of Medicine, University of Louisville, Louisville, Kentucky, USA.
Sadeer Al-KindiDivision of Cardiology, Department of Medicine, University Hospitals, Harrington Heart and Vascular Institute, Case Western Reserve University, Cleveland, Ohio, USA.
Shady AbohashemDivison of Cardiovascular Imaging, Radiology Department, Massachusetts General Hospital-Harvard Medical School, Boston, Massachusetts, USA.
Colin T PhillipsDepartment of Cardiology, Maine Medical Center, Portland, Maine, USA.
Jamal S RanaThe Permanente Medical Group, Department of Cardiology, Oakland Medical Center, Oakland, California, USA.
Aruni BhatnagarDivision of Environmental Medicine, Department of Medicine, University of Louisville, Louisville, Kentucky, USA.
Martha GulatiDepartment of Cardiology, Barbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Sanjay RajagopalanDivision of Cardiology, Department of Medicine, University Hospitals, Harrington Heart and Vascular Institute, Case Western Reserve University, Cleveland, Ohio, USA.
Dinesh K KalraDivision of Cardiology, Department of Medicine, University of Louisville, Louisville, Kentucky, USA.

Funding

Superfund Training CoreP42ES023716 · NIEHS · UNIVERSITY OF LOUISVILLE · PI HEIN, DAVID W · 2017 to 2025
$18.1M
University of Louisville Center for Integrative Environmental Health SciencesP30ES030283 · NIEHS · UNIVERSITY OF LOUISVILLE · PI Amanda Jo LeBlanc · 2020 to 2026
$10.0M
Urban Greenness and Cardiovascular HealthR01ES029846 · NIEHS · UNIVERSITY OF LOUISVILLE · PI Aruni Bhatnagar · 2018 to 2026
$6.2M
Diversity Suppplement (CIRCADIAN) Circadian Disruption as Mediator of Cardiometabolic Risk in Air PollutionR35ES031702 · NIEHS · CASE WESTERN RESERVE UNIVERSITY · PI Sanjay Rajagopalan · 2021 to 2026
$5.9M
NIEHS NIH HHS P30 ES030283NIEHS NIH HHS P42 ES023716NIEHS NIH HHS R01 ES029846NIEHS NIH HHS R35 ES031702
6 · The paper itself

Abstract

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Over the past 50 years, there has been a substantial decline in the incidence of CVD and related mortality in high-income countries, largely due to the mitigation of modifiable risk factors such as smoking, hypertension, and diabetes. However, a significant burden of CVD remains in low- to middle-income countries, despite their lower prevalence of traditional risk factors; other environmental factors, particularly pollution, play a significant role in this attributable risk. Mounting evidence underscores a strong association between pollution and adverse health effects, including CVD. This article is part 1 of a 2-part state-of-the-art review and discusses air pollution and its adverse effects on CVD, highlighting pathophysiological mechanisms and methods to reduce air pollution and exposure to these pollutants.

Indexed as

air pollutionglobal burden of diseaseparticulate matter

Identifiers

PMID38939391
PMCPMC11198409

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.