Evidence map›Paper›PMID 38939312›Full record

ArticleJACC. Advances2022

Cumulative In-Hospital Costs Associated With Single-Ventricle Palliation.

Michael L O'Byrne, Kimberly E McHugh, Jing Huang, Lihai Song, Heather Griffis, Brett R Anderson, Emily M Bucholz, Nikhil K Chanani, Justin J Elhoff, Stephanie S Handler and 9 more

Abstract read
In one paragraph

Article in JACC. Advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Michael L O'ByrneDivision of Cardiology, The Children's Hospital of Philadelphia and Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Kimberly E McHughDivision of Cardiology, Medical University of South Carolina, Charleston, South Carolina, USA.
Jing HuangDivision of Cardiology, The Children's Hospital of Philadelphia and Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Lihai SongData Science and Biostatistics Unit, Department of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Heather GriffisData Science and Biostatistics Unit, Department of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Brett R AndersonDivision of Cardiology, New York-Presbyterian Morgan-Stanley Children's Hospital/Columbia University Irving Medical Center, New York, New York, USA.
Emily M BucholzDepartment of Cardiology, Children's Hospital Boston and Harvard University Medical School, Boston, Massachusetts, USA.
Nikhil K ChananiChildren's Healthcare of Atlanta, Sibley Heart Center and Emory University School of Medicine, Atlanta, Georgia, USA.
Justin J ElhoffSections of Critical Care and Cardiology, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas, USA.
Stephanie S HandlerChildren's Hospital of Wisconsin, Milwaukee, Wisconsin, USA.
Jeffery P JacobsDivision of Cardiothoracic Surgery, Departments of Surgery and Pediatrics, Congenital Heart Center, University of Florida, Gainesville, Florida, USA.
Jennifer S LiDivision of Pediatric Cardiology, Duke University School of Medicine, Durham, North Carolina, USA.
Alan B LewisDivision of Cardiology, Department of Pediatrics, Children's Hospital of Los Angeles, Keck School of Medicine of University of Southern California, Los Angeles, California, USA.
Brian W McCrindleDepartment of Pediatrics, Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Nelangi M PintoDivision of Cardiology, Primary Children's Hospital and University of Utah School of Medicine, Salt Lake City, Utah, USA.
Peter SassalosDivision of Pediatric Cardiothoracic Surgery, C.S. Mott Children's Hospital and University of Michigan School of Medicine, Ann Arbor, Michigan, USA.
David S SparThe Heart Institute, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA.
Sara K PasqualiDivision of Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Andrew C GlatzDivision of Cardiology, The Children's Hospital of Philadelphia and Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Funding

RESEARCH METHODS IN PEDIATRICS HEART DISEASET32HL007572 · NHLBI · CHILDREN'S HOSPITAL BOSTON · PI Sarah D DE FERRANTI, Jane W. Newburger · 1985 to 2026
$13.0M
NHLBI NIH HHS T32 HL007572
6 · The paper itself

Abstract

Background: In the SVR (Single Ventricle Reconstruction) Trial, 1-year survival in recipients of right ventricle to pulmonary artery shunts (RVPAS) was superior to that in those receiving modified Blalock-Taussig-Thomas shunts (MBTTS), but not in subsequent follow-up. Cost analysis is an expedient means of evaluating value and morbidity. Objectives: The purpose of this study was to evaluate differences in cumulative hospital costs between RVPAS and MBTTS. Methods: Clinical data from SVR and costs from Pediatric Health Information Systems database were combined. Cumulative hospital costs and cost-per-day-alive were compared serially at 1, 3, and 5 years between RVPAS and MBTTS. Potential associations between patient-level factors and cost were explored with multivariable models. Results: In total, 303 participants (55% of the SVR cohort) from 9 of 15 sites were studied (48% MBTTS). Observed total costs at 1 year were lower for MBTTS ($701,260 ± 442,081) than those for RVPAS ($804,062 ± 615,068), a difference that was not statistically significant ( Conclusions: Total costs do not differ significantly between MBTTS and RVPAS. The magnitude of longitudinal costs underscores the importance of efforts to improve outcomes in this vulnerable population.

Indexed as

economic analysishypoplastic left heart syndromeoutcomes researchpediatrics

Identifiers

PMID38939312
PMCPMC11198056

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.