Evidence map›Paper›PMID 38939126›Full record

ArticleChemical science2024

Peptide macrocyclisation

Frances R Smith, Declan Meehan, Rhys C Griffiths, Harriet J Knowles, Peiyu Zhang, Huw E L Williams, Andrew J Wilson, Nicholas J Mitchell

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Frances R SmithSchool of Chemistry, University of Nottingham, University Park Nottingham NG7 2RD UK nicholas.mitchell@nottingham.ac.uk.
Declan MeehanSchool of Chemistry, University of Nottingham, University Park Nottingham NG7 2RD UK nicholas.mitchell@nottingham.ac.uk.
Rhys C GriffithsSchool of Chemistry, University of Nottingham, University Park Nottingham NG7 2RD UK nicholas.mitchell@nottingham.ac.uk.
Harriet J KnowlesSchool of Chemistry, University of Nottingham, University Park Nottingham NG7 2RD UK nicholas.mitchell@nottingham.ac.uk.
Peiyu ZhangSchool of Chemistry, University of Leeds Woodhouse Lane Leeds LS2 9JT UK.
Huw E L WilliamsBiodiscovery Institute, University of Nottingham, University Park Nottingham NG7 2RD UK.ORCID https://orcid.org/0000-0002-2623-6287
Andrew J WilsonSchool of Chemistry, University of Leeds Woodhouse Lane Leeds LS2 9JT UK.ORCID https://orcid.org/0000-0001-9852-6366
Nicholas J MitchellSchool of Chemistry, University of Nottingham, University Park Nottingham NG7 2RD UK nicholas.mitchell@nottingham.ac.uk.ORCID https://orcid.org/0000-0002-9041-1852

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic methods that enable the macrocyclisation of peptides facilitate the development of effective therapeutic and diagnostic tools. Herein we report a peptide cyclisation strategy based on intramolecular interception of visible-light-mediated cysteine desulfurisation. This method allows cyclisation of unprotected peptides in an aqueous solution

Identifiers

PMID38939126
PMCPMC11206203

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.