Evidence map›Paper›PMID 38939064›Full record

ArticlePrzeglad gastroenterologiczny2024

Associations of oxidative stress, metabolic disorders in colorectal cancer patients.

Konrad Zaręba, Justyna Dorf, Kerianne Cummings, Seena Tabibi, Mateusz Maciejczyk, Bogusław Kędra

Abstract read
In one paragraph

Article in Przeglad gastroenterologiczny, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Konrad Zaręba2 Clinical Department of General, Gastroenterological and Oncological Surgery, Medical University of Bialystok, Bialystok, Poland.
Justyna DorfDepartment of Clinical Laboratory Diagnostics, Medical University of Bialystok, Bialystok, Poland.
Kerianne CummingsStudents' Scientific Association, 2nd Clinical Department of General, Gastroenterological and Oncological Surgery, Medical University of Bialystok, Bialystok, Poland.
Seena TabibiDepartment of Pathology, The Johns Hopkins University School of Medicine, Baltimore, USA.
Mateusz MaciejczykDepartment of Hygiene and Epidemiology, Medical University of Bialystok, Bialystok, Poland.
Bogusław Kędra2 Clinical Department of General, Gastroenterological and Oncological Surgery, Medical University of Bialystok, Bialystok, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Colorectal cancer have been one of the most common malignant neoplasm in the world. In most patients with this cancer, we can observe both redox homeostasis and nutritional disorders. Aim: To assess the occurrence of oxidative stress in patients with colorectal cancer and its severity depending on the nutritional status of patients. Material and methods: The study group consisted of 50 patients with colorectal cancer. In the control group, samples were obtained from 40 healthy subjects. Basal metabolic index and nutrition risk screening (NRS) 2002 scale was completed. The total antioxidant capacity (TAC), total oxidant status (TOS), malondialdehyde (MDA) were determined yielding the oxidative stress index (OSI) determined by the TOS/TAC ratio and TAC/MDA ratio. Results: There were statistically significant differences ( Conclusions: Neoplastic disease, such as colorectal cancer, precipitates an increase in oxidative stress. Concurrently, the nutritional status of patients, especially malnutrition, further intensifies this process.

Indexed as

colorectal cancermetabolic disordersoxidative stresstotal antioxidant capacity

Identifiers

PMID38939064
PMCPMC11200079

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.