Evidence map›Paper›PMID 38938996›Full record

ArticleJACC. Advances2023

Association Between Progression of Arterial Stiffness and Left Ventricular Remodeling in a Community-Based Cohort.

Yuriko Yoshida, Koki Nakanishi, Zhezhen Jin, Masao Daimon, Jumpei Ishiwata, Naoko Sawada, Megumi Hirokawa, Hidehiro Kaneko, Tomoko Nakao, Yoshiko Mizuno and 4 more

Abstract read
In one paragraph

Article in JACC. Advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Changes in segmental arterial stiffness and volume dynamics across the arterial tree during noradrenaline administration in rabbits.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yuriko YoshidaDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Koki NakanishiDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Zhezhen JinDepartment of Biostatistics, Columbia University, New York, New York, USA.
Masao DaimonDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Jumpei IshiwataDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Naoko SawadaDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Megumi HirokawaDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Hidehiro KanekoDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Tomoko NakaoDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Yoshiko MizunoDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Hiroyuki MoritaDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Marco R Di TullioDepartment of Medicine, Columbia University, New York, New York, USA.
Shunichi HommaDepartment of Medicine, Columbia University, New York, New York, USA.
Issei KomuroDepartment of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cross sectionally measured, elevated arterial stiffness is associated with unfavorable left ventricular (LV) remodeling, suggesting its important role in the pathophysiology of heart failure. However, data linking the degree of arterial stiffness progression with LV remodeling are scarce. Objectives: The purpose of this study was to investigate the association between longitudinal change in arterial stiffness and changes in LV remodeling. Methods: Serial measurements of arterial stiffness by cardio-ankle vascular index (CAVI) were performed in 317 participants without cardiovascular disease and with normal arterial stiffness. LV size, mass, and function were assessed by transthoracic echocardiography and including LV global longitudinal strain (LVGLS) by speckle-tracking and tissue Doppler velocity (e') of the mitral annulus (diastolic function). Results: During a median follow-up of 26.8 mo, there was a significant increase in CAVI ( Conclusions: Longitudinal increase in arterial stiffness is associated with deterioration in LVGLS. Vascular-ventricular coupling plays an important role in the progressive decline in ventricular function even at an early, subclinical stage.

Indexed as

arterial stiffnesscardio-ankle vascular indexglobal longitudinal strainleft ventricular functionsex-differences

Identifiers

PMID38938996
PMCPMC11198086

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.