Evidence map›Paper›PMID 38938994›Full record

ArticleJACC. Advances2023

Obesity Cardiomyopathy in Sudden Cardiac Death: A Distinct Entity? A Comparative Study.

Joseph Westaby, Chiara Dalle-Carbonare, Irina Chis Ster, Mary N Sheppard

Abstract read
In one paragraph

Article in JACC. Advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joseph WestabyCardiovascular Clinical Academic Group and Cardiology Research Section, CRY Centre for Cardiovascular Pathology, Molecular and Clinical Sciences Research Institute, St. George's University of London and St George's University Hospitals NHS Foundation Trust, London, United Kingdom.
Chiara Dalle-CarbonareCardiovascular Clinical Academic Group and Cardiology Research Section, CRY Centre for Cardiovascular Pathology, Molecular and Clinical Sciences Research Institute, St. George's University of London and St George's University Hospitals NHS Foundation Trust, London, United Kingdom.
Irina Chis SterInfection and Immunity Research Institute, St George's University of London, London, United Kingdom.
Mary N SheppardCardiovascular Clinical Academic Group and Cardiology Research Section, CRY Centre for Cardiovascular Pathology, Molecular and Clinical Sciences Research Institute, St. George's University of London and St George's University Hospitals NHS Foundation Trust, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Obesity cardiomyopathy (OCM) can be associated with sudden cardiac death (SCD) but its pathologic features are not well described. Objectives: The objective of this study was to characterize the clinical and pathological features of OCM associated with SCD. Methods: This was a retrospective case control autopsy study. OCM was identified by an increased heart weight (>550 g in males; >450 g in females) in individuals with obesity (body mass index [BMI] ≥30 kg/m Results: Of 6,457 SCD cases, 53 cases of OCM were identified and matched to 106 controls with obesity and 106 normal weight controls. The OCM mean age at death of individuals with OCM was 42 ± 12 with a male predominance (n = 34, 64%). Males died younger than females (40 ± 13 vs 45 ± 10, Conclusions: OCM may be a specific pathological entity associated with SCD. It is most commonly seen in young males with increased BMI.

Indexed as

epicardial fathypertrophyobesity cardiomyopathypathologysudden cardiac death

Identifiers

PMID38938994
PMCPMC11198605

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.