ArticleJACC. Advances2023
Impaired Exercise Capacity and Mortality Risk in Adults With Congenital Heart Disease.
Article in JACC. Advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effect of inspiratory muscle training on the inspiratory muscle metaboreflex: A systematic review.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2025Pooled it
- Empowering congenital heart disease treatment: Physical activity prescription. The Italian proposal.International journal of cardiology. Congenital heart disease · 2026Article
- Outcome 50 years after surgical repair of pulmonary valve stenosis: a longitudinal cohort study.BMJ open · 2026Article
- Article
- How does regular exercise improve cardiovascular function: Congenital heart disease and beyond.International journal of cardiology. Congenital heart disease · 2025Review
- Sedentary behavior and physical activity on exercise capacity in adult patients with congenital heart disease.International journal of cardiology. Congenital heart disease · 2025Article
- Physiological responses of children with surgically corrected congenital heart disease during high-altitude trekking: an exploratory observational study.Frontiers in pediatrics · 2025Article
- Prognostic value of cardiopulmonary exercise test in children with congenital heart defects.Open heart · 2024Article
- Biking More With Congenital Heart Disease: Stratifying Risk in the New Generation of Adult Patients.JACC. Advances · 2023Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: An association between impaired exercise capacity and risk of mortality has been reported among adults with congenital heart disease (CHD). Over the years, treatment methods have improved and may influence outcome. Hence, we report data from a national cohort reflecting a contemporary population. Objectives: The purpose of this study was to investigate the association between exercise capacity (workload) and mortality in a large registry-based cohort. Methods: Data on exercise capacity using cycle ergometer were retrieved from the national registry of CHD. The association between predicted exercise capacity (%EC Results: In total, 3,721 adults (>18 years, 44.6% women) with CHD were included. The median age was 27.0 years (IQR: 20.8-41.0 years) and mean %EC Conclusions: Impaired exercise capacity and CHD complexity are independently associated with all-cause mortality in patients with CHD. Exercise capacity is an easily accessible variable that may be a useful tool for risk assessment in adult patients with CHD, but this needs confirmation in prospective studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.