Evidence map›Paper›PMID 38938894›Full record

ArticleOpen forum infectious diseases2024

β-Lactamase and Macrolide Resistance Gene Carriage in

Polycarp Mogeni, Olusegun O Soge, Kirkby D Tickell, Stephanie N Tornberg, Rushlenne Pascual, Erika Wakatake, Mame M Diakhate, Doreen Rwigi, Kevin Kariuki, Samuel Kariuki and 4 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Polycarp MogeniCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.ORCID https://orcid.org/0000-0003-1926-7576
Olusegun O SogeDepartment of Global Health, University of Washington, Seattle, Washington, USA.
Kirkby D TickellDepartment of Global Health, University of Washington, Seattle, Washington, USA.
Stephanie N TornbergDepartment of Global Health, University of Washington, Seattle, Washington, USA.
Rushlenne PascualDepartment of Global Health, University of Washington, Seattle, Washington, USA.
Erika WakatakeDepartment of Global Health, University of Washington, Seattle, Washington, USA.
Mame M DiakhateDepartment of Global Health, University of Washington, Seattle, Washington, USA.
Doreen RwigiCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Kevin KariukiCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Samuel KariukiCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Benson O SingaCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Ferric C FangDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.
Judd L WalsonDepartment of Global Health, University of Washington, Seattle, Washington, USA.
Patricia B PavlinacDepartment of Global Health, University of Washington, Seattle, Washington, USA.

Funding

The role of enteric pathogens and antimicrobial resistance in driving clinical and nutritional deterioration, and azithromycin's potential effect, among children discharged from hospital in KenyaR01AI150978 · NIAID · UNIVERSITY OF WASHINGTON · PI PAVLINAC, PATRICIA · 2020 to 2024
$3.7M
NIAID NIH HHS R01 AI150978
6 · The paper itself

Abstract

Background: Antimicrobial resistance (AMR) is a global threat to infectious disease control, particularly among recently hospitalized children. We sought to determine the prevalence and mitigating factors of resistance in enteric Methods: Between June 2016 and November 2019, children aged 1 to 59 months were enrolled at the point of discharge from the hospital. Results: Of the 238 children whose Conclusions: Among children discharged from the hospital, history of vaccination, shorter hospital stay, lack of in-hospital antibiotic exposure, and improved sanitation were associated with a lower likelihood of AMR genes. To mitigate the continued spread of AMR, AMR control programs should consider strategies beyond antimicrobial stewardship, including improvements in sanitation, increased vaccine coverage, and the development of novel vaccines.

Indexed as

CTX-Mhospitalmph(A)routine vaccinationβ-lactamase

Identifiers

PMID38938894
PMCPMC11210497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.