ArticleJACC. Advances2024
Association Between Frailty and Management and Outcomes of Acute Myocardial Infarction Complicated by Cardiogenic Shock.
Article in JACC. Advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Longitudinal Changes in Frailty and Major Adverse Cardiovascular Events in Patients With Coronary Heart Disease.Journal of the American Heart Association · 2026Article
- Simulation study of frailty as a baseline confounder: the need to improve reporting intensive care trials.Critical care (London, England) · 2026Review
- Cardiogenic Shock: Outcome Patterns Across the Body Mass Spectrum and Renal Vulnerability.Cardiology · 2026Article
- Frailty and long-term mortality in cardiogenic shock: a binational multicentre cohort study.Critical care (London, England) · 2026Article
- In-hospital outcomes of intravascular lithotripsy compared to rotational atherectomy and cutting/scoring balloon angioplasty.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Frailty Modifies the Prognostic Effect of Age Among Older Adults With Acute Coronary Syndrome.Journal of the American Heart Association · 2026Observational
- Baseline and 72-h dynamic laboratory deficit burden for mortality through day 90 after acute ischemic stroke in critical care: landmark analyses with temporal validation.Frontiers in neurology · 2026Article
- The effects of invasive treatment on patients with frailty and non-ST-segment elevation myocardial infarction.Scientific reports · 2025Article
- The Impact of Combining CIRS-G and Clinical Frailty Score on One-Month Mortality in Acute Coronary Syndrome.Healthcare (Basel, Switzerland) · 2025Article
- Impact of Adjuvant Mannitol Administration on the Development of Delirium in Patients with Myocardial Infarction: Results of a Single-Center Pilot Study.Journal of clinical medicine · 2025Article
- AI-Based Predictive Models for Cardiogenic Shock in STEMI: Real-World Data for Early Risk Assessment and Prognostic Insights.Journal of clinical medicine · 2025Article
- Relationship Between Perceived Social Support and Physical Frailty Among Older Patients with Coronary Artery Disease: A Dual Mediation Model.Journal of clinical medicine · 2025Article
- Survivorship After Cardiogenic Shock.Circulation · 2025Review
- A Delicate Matter: The Burden of Frailty on AMI-CS.JACC. Advances · 2024Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Background: Cardiogenic shock (CS) in the setting of acute myocardial infarction (AMI) is associated with high morbidity and mortality. Frailty is a common comorbidity in patients with cardiovascular disease and is also associated with adverse outcomes. The impact of preexisting frailty at the time of CS diagnosis following AMI has not been studied. Objectives: The purpose of this study was to examine the prevalence of frailty in patients admitted with AMI complicated by CS (AMI-CS) hospitalizations and its associations with in-hospital outcomes. Methods: We retrospectively analyzed the National Inpatient Sample from 2016 to 2020 and identified all hospitalizations for AMI-CS. We classified them into frail and nonfrail groups according to the hospital frailty risk score cut-off of 5 and compared in-hospital outcomes. Results: A total of 283,700 hospitalizations for AMI-CS were identified. Most (70.8%) occurred in the frail. Those with frailty had higher odds of in-hospital mortality (adjusted OR [aOR]: 2.17, 95% CI: 2.07 to 2.26, Conclusions: A high proportion of hospitalizations for AMI-CS had concomitant frailty. Hospitalizations with AMI-CS and frailty had higher rates of in-hospital morbidity and mortality compared to those without frailty.
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