Evidence map›Paper›PMID 38938841›Full record

ArticleJACC. Advances2024

Effect of Sex and Flow Status on Outcomes After Surgical or Transcatheter Aortic Valve Replacement.

Rasmus Carter-Storch, Rebecca T Hahn, Amr E Abbas, Melissa A Daubert, Pamela S Douglas, Sammy Elmariah, Yanglu Zhao, Michael J Mack, Martin B Leon, Philippe Pibarot and 1 more

Abstract read
In one paragraph

Article in JACC. Advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Observational
  3. Review
  4. Understanding Aortic Stenosis and Transcatheter Aortic Valve Replacement in Women.Structural heart : the journal of the Heart Team · 2025
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rasmus Carter-StorchInstitut Universitaire de Cardiologie et de Pneumologie de Québec/Quebec Heart and Lung Institute, Laval University, Quebec, Quebec, Canada.
Rebecca T HahnDepartment of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Amr E AbbasCorewell Health, William Beaumont University Hospital, Royal Oak, Michigan, USA.
Melissa A DaubertDuke University, Durham, North Carolina, USA.
Pamela S DouglasDuke University, Durham, North Carolina, USA.
Sammy ElmariahMassachusetts General Hospital, Boston, Massachusetts, USA.
Yanglu ZhaoEdwards Lifesciences, Irvine, California, USA.
Michael J MackBaylor Scott & White Health, Plano, Texas, USA.
Martin B LeonColumbia University, New York, New York, USA.
Philippe PibarotInstitut Universitaire de Cardiologie et de Pneumologie de Québec/Quebec Heart and Lung Institute, Laval University, Quebec, Quebec, Canada.
Marie-Annick ClavelInstitut Universitaire de Cardiologie et de Pneumologie de Québec/Quebec Heart and Lung Institute, Laval University, Quebec, Quebec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Low stroke volume index <35 ml/m Objectives: The purpose of this study was to analyze the risk associated with PLF in severe aortic stenosis for men and women randomized to TAVR or SAVR. Methods: Patients with ejection fraction ≥50% from the PARTNER (Placement of Aortic Transcatheter Valves) 2 and 3 trials were stratified by sex and treatment arm. The impact of PLF on the 2-year occurrence of the composite of death or heart failure hospitalization (primary endpoint) and of all-cause mortality alone (secondary endpoint) was analyzed. Analysis of variance was used to assess baseline differences between groups. Multivariate Cox regression analysis was used to identify predictors of the endpoint. Results: Out of 2,242 patients, PLF was present in 390 men and 239 women (30% vs 26%, Conclusions: In women with PLF, TAVR may improve outcomes compared to SAVR. PLF appears to have less impact on outcomes in men.

Indexed as

low flow aortic stenosisSAVRsex-differencesTAVR

Identifiers

PMID38938841
PMCPMC11198680

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.