Evidence map›Paper›PMID 38938781›Full record

ReviewFrontiers in neurology2024

Advances in novel biomaterials combined with traditional Chinese medicine rehabilitation technology in treatment of peripheral nerve injury.

Xinhao Liu, Zekai Hu, Yixiao Huang, Lelun Hu, Jinnuo Lu, Mengning Chen, Han Xue, Shujie Ma, Jie Wan, Jun Hu

Abstract readReview
In one paragraph

Review in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xinhao Liu *The Second Rehabilitation Hospital of Shanghai, Shanghai, China.
Zekai Hu *The Second Rehabilitation Hospital of Shanghai, Shanghai, China.
Yixiao HuangShanghai University of Traditional Chinese Medicine, Shanghai, China.
Lelun HuShanghai University of Traditional Chinese Medicine, Shanghai, China.
Jinnuo LuShanghai University of Traditional Chinese Medicine, Shanghai, China.
Mengning ChenShanghai University of Traditional Chinese Medicine, Shanghai, China.
Han XueShanghai University of Traditional Chinese Medicine, Shanghai, China.
Shujie MaThe Second Rehabilitation Hospital of Shanghai, Shanghai, China.
Jie WanShanghai University of Traditional Chinese Medicine, Shanghai, China.
Jun HuThe Second Rehabilitation Hospital of Shanghai, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripheral nerve injuries (PNI) represent one of the primary neuropathies leading to lifelong disability. Nerve regeneration and targeted muscle atrophy stand as the two most crucial factors influencing functional rehabilitation post peripheral nerve injury. Over time, traditional Chinese medicine (TCM) rehabilitation approaches such as acupuncture, Tuina, and microneedles serve as pivot means to activate the regeneration of injured nerve Schwann cells. By promoting axon regeneration, these approaches can accomplish nerve repair, reconstruction, and functional rehabilitation. Although TCM rehabilitation approaches have clinically demonstrated effectiveness in promoting the repair and regeneration of PNI, the related molecular mechanisms remain unclear. This significantly hampers the application and promotion of TCM rehabilitation in PNI recovery. Therefore, deeply delving into the cellular and molecular mechanisms of TCM rehabilitation technologies to foster nerve regeneration stands as the most pressing issue. On the other hand, in recent years, novel biomaterials represented by hydrogels, microfluidic platforms, and new chitosan scaffolds have showed their unique roles in treating various degrees of nerve injury. These methods exhibit immense potential in conducting high-throughput cell and organoid culture

Indexed as

microfluidic chipnovel biomaterialsperipheral nerve injuryrehabilitationtraditional Chinese medicine

Identifiers

PMID38938781
PMCPMC11208681

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.