Evidence map›Paper›PMID 38938720›Full record

ArticleJACC. Advances2023

Sex Differences in DeBakey Type I/II Acute Aortic Dissection Outcomes: The Tokyo Acute Aortic Super-network.

Toshiyuki Takahashi, Hideaki Yoshino, Tomoki Shimokawa, Hitoshi Ogino, Takashi Kunihara, Koichi Akutsu, Michio Usui, Manabu Yamasaki, Kazuhiro Watanabe, Mitsuhiro Kawata and 9 more

Abstract read
In one paragraph

Article in JACC. Advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Sex-Based Differences in Dissection Patterns and Surgical Strategies in Tear-Oriented Repair for Acute Type A Aortic Dissection: A Single-Center Retrospective Study.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2026
    Article
  2. Staged hybrid approach for acute type A aortic dissection: zone 2 arch replacement and completion thoracic endovascular aortic repair upon indication.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Toshiyuki TakahashiTokyo CCU Network Scientific Committee, Tokyo, Japan.
Hideaki YoshinoTokyo CCU Network Scientific Committee, Tokyo, Japan.
Tomoki ShimokawaTokyo CCU Network Scientific Committee, Tokyo, Japan.
Hitoshi OginoTokyo CCU Network Scientific Committee, Tokyo, Japan.
Takashi KuniharaTokyo CCU Network Scientific Committee, Tokyo, Japan.
Koichi AkutsuTokyo CCU Network Scientific Committee, Tokyo, Japan.
Michio UsuiTokyo CCU Network Scientific Committee, Tokyo, Japan.
Manabu YamasakiTokyo CCU Network Scientific Committee, Tokyo, Japan.
Kazuhiro WatanabeTokyo CCU Network Scientific Committee, Tokyo, Japan.
Mitsuhiro KawataTokyo CCU Network Scientific Committee, Tokyo, Japan.
Takeshiro FujiiTokyo CCU Network Scientific Committee, Tokyo, Japan.
Hiroshi MasuharaTokyo CCU Network Scientific Committee, Tokyo, Japan.
Tomomitsu TakagiTokyo CCU Network Scientific Committee, Tokyo, Japan.
Tomohiro ImazuruTokyo CCU Network Scientific Committee, Tokyo, Japan.
Takeshi YamamotoTokyo CCU Network Scientific Committee, Tokyo, Japan.
Ken NagaoTokyo CCU Network Scientific Committee, Tokyo, Japan.
Shun KohsakaTokyo CCU Network Scientific Committee, Tokyo, Japan.
Morimasa TakayamaTokyo CCU Network Scientific Committee, Tokyo, Japan.
Tokyo CCU Network Scientific Committee

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sex differences in the clinical presentation and outcomes of DeBakey type I/II (Stanford type A) acute aortic dissection (AAD) remain unclear. Objectives: The authors aimed to determine the impact of sex on the clinical presentation and in-hospital outcomes of surgically or medically treated patients with type I/II AAD. Methods: We studied 3,089 patients with type I/II AAD enrolled in multicenter Japanese registry between 2013 and 2018. The patients were divided into 2 treatment groups: surgical and medical. Multivariable logistic regression was used to examine the association between sex and in-hospital mortality. Results: In the entire cohort, women were older and more likely to have hyperlipidemia, previous stroke, altered consciousness, and shock/hypotension at presentation than men. Women had higher proportions of intramural hematomas and type II dissections than men. In the surgical group (n = 2,543), men had higher rates of preoperative end-organ malperfusion ( Conclusions: Male sex was associated with higher in-hospital mortality for type I/II AAD in the surgical group but not in the medical group. Further research is needed to understand the mechanisms responsible for worse surgical outcomes in men.

Indexed as

aortic dissectionmortalitysex differencestanford type Asurgical repair

Identifiers

PMID38938720
PMCPMC11198475

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.