Article in Neurology. Clinical practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
11 authors.
Xiaoyang LiDepartment of Neurology (XL, PG, KMS, MR, AZ, EPF, A. McKeon, SJP, JWB, DD); Department of Radiology (A. Madhavan); and Department of Pathology and Laboratory Medicine (AZ, EPF, A. McKeon, SJP, DD), Mayo Clinic, Rochester, MN.ORCID https://orcid.org/0000-0003-3741-3688
Pranjal GuptaDepartment of Neurology (XL, PG, KMS, MR, AZ, EPF, A. McKeon, SJP, JWB, DD); Department of Radiology (A. Madhavan); and Department of Pathology and Laboratory Medicine (AZ, EPF, A. McKeon, SJP, DD), Mayo Clinic, Rochester, MN.ORCID https://orcid.org/0009-0000-8482-8259
Kelsey M SmithDepartment of Neurology (XL, PG, KMS, MR, AZ, EPF, A. McKeon, SJP, JWB, DD); Department of Radiology (A. Madhavan); and Department of Pathology and Laboratory Medicine (AZ, EPF, A. McKeon, SJP, DD), Mayo Clinic, Rochester, MN.ORCID https://orcid.org/0000-0001-8659-3801
Ajay MadhavanDepartment of Neurology (XL, PG, KMS, MR, AZ, EPF, A. McKeon, SJP, JWB, DD); Department of Radiology (A. Madhavan); and Department of Pathology and Laboratory Medicine (AZ, EPF, A. McKeon, SJP, DD), Mayo Clinic, Rochester, MN.ORCID https://orcid.org/0000-0003-1794-4502
Mohamed RezkDepartment of Neurology (XL, PG, KMS, MR, AZ, EPF, A. McKeon, SJP, JWB, DD); Department of Radiology (A. Madhavan); and Department of Pathology and Laboratory Medicine (AZ, EPF, A. McKeon, SJP, DD), Mayo Clinic, Rochester, MN.ORCID https://orcid.org/0009-0001-8560-3550
Anastasia ZekeridouDepartment of Neurology (XL, PG, KMS, MR, AZ, EPF, A. McKeon, SJP, JWB, DD); Department of Radiology (A. Madhavan); and Department of Pathology and Laboratory Medicine (AZ, EPF, A. McKeon, SJP, DD), Mayo Clinic, Rochester, MN.ORCID https://orcid.org/0000-0002-1960-9065
Eoin P FlanaganDepartment of Neurology (XL, PG, KMS, MR, AZ, EPF, A. McKeon, SJP, JWB, DD); Department of Radiology (A. Madhavan); and Department of Pathology and Laboratory Medicine (AZ, EPF, A. McKeon, SJP, DD), Mayo Clinic, Rochester, MN.ORCID https://orcid.org/0000-0002-6661-2910
Andrew McKeonDepartment of Neurology (XL, PG, KMS, MR, AZ, EPF, A. McKeon, SJP, JWB, DD); Department of Radiology (A. Madhavan); and Department of Pathology and Laboratory Medicine (AZ, EPF, A. McKeon, SJP, DD), Mayo Clinic, Rochester, MN.ORCID https://orcid.org/0000-0001-6856-8143
Sean J PittockDepartment of Neurology (XL, PG, KMS, MR, AZ, EPF, A. McKeon, SJP, JWB, DD); Department of Radiology (A. Madhavan); and Department of Pathology and Laboratory Medicine (AZ, EPF, A. McKeon, SJP, DD), Mayo Clinic, Rochester, MN.ORCID https://orcid.org/0000-0002-6140-5584
Jeffrey W BrittonDepartment of Neurology (XL, PG, KMS, MR, AZ, EPF, A. McKeon, SJP, JWB, DD); Department of Radiology (A. Madhavan); and Department of Pathology and Laboratory Medicine (AZ, EPF, A. McKeon, SJP, DD), Mayo Clinic, Rochester, MN.ORCID https://orcid.org/0000-0002-0147-8159
Divyanshu DubeyDepartment of Neurology (XL, PG, KMS, MR, AZ, EPF, A. McKeon, SJP, JWB, DD); Department of Radiology (A. Madhavan); and Department of Pathology and Laboratory Medicine (AZ, EPF, A. McKeon, SJP, DD), Mayo Clinic, Rochester, MN.ORCID https://orcid.org/0000-0001-6865-9045
Funding
Seronegative Autoimmune Encephalopathies: Biomarker Discovery, Validation & Deep PhenotypingR01NS126227 · NINDS · MAYO CLINIC ROCHESTER · PI Andrew McKeon · 2022 to 2026
$1.9M
NINDS NIH HHS R01 NS126227
6 · The paper itself
Abstract
Objectives: To study the frequency, causes, and consequences of seizure-related falls and near falls in LGI1-IgG autoimmune encephalitis. Methods: We retrospectively reviewed 136 patients seen at Mayo Clinic with (1) LGI1-IgG seropositivity, (2) clinical phenotypes compatible with LGI1-IgG autoimmune encephalitis, and (3) falls or near falls related to seizures. The clinical documentation, MRI, and EEG data were collected and reviewed. Results: In this cohort of 136 patients, 27% (n = 36) had falls or near falls related to seizures. The median age was 67 years (range 49-86 years) and 23/36 (64%) were male. Facio-brachio-crural dystonic seizures (21/36, 58%) and drop attacks (9/36, 25%) were the most common causes. Seizure-related falls resulted in injuries in 18/30 (60%), ranging from skin lacerations, joint dislocations, bone fractures to life-threatening intracranial hemorrhage. The injuries occurred most with drop attacks 8/9 (89%). Seizure-related falls or near falls resolved with immunotherapy in 24/32 (75%) whereas the responsiveness to anti-seizure medication alone was poor (4/32, 13%). Discussion: Our study demonstrates that seizure-related falls and near falls are common in LGI1-IgG autoimmune encephalitis. Early diagnosis, prompt immunotherapy initiation, and proper counseling are key to improving functional outcomes and preventing secondary injuries.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Seizure-Related Falls and Near Falls in LGI1-IgG Autoimmune Encephalitis. · full record | OpenQuestion