Evidence map›Paper›PMID 38938524›Full record

ArticleAdvanced optical materials2022

True FRET-based sensing of pH via Separation of FRET and Photon Reabsorption.

Conrad Corbella Bagot, Eric Rappeport, Ananda Das, Taleb BaTis, Wounjhang Park

Abstract read
In one paragraph

Article in Advanced optical materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Conrad Corbella BagotUniversity of Colorado, Department of Electrical, Computer, and Energy Engineering.
Eric RappeportUniversity of Colorado, Department of Electrical, Computer, and Energy Engineering.
Ananda DasUniversity of Colorado, Department of Physics.
Taleb BaTisUniversity of Colorado, Materials Science and Engineering Program.
Wounjhang ParkUniversity of Colorado, Department of Electrical, Computer, and Energy Engineering.

Funding

Optical nanosensor for 3D force sensing in intact tissues of live animalsR21GM140347 · NIGMS · UNIVERSITY OF COLORADO · PI PARK, WOUNJHANG · 2021 to 2022
$425k
NIGMS NIH HHS R21 GM140347
6 · The paper itself

Abstract

Förster Resonance Energy Transfer (FRET)-based devices have been extensively researched as potential biosensors due to their highly localized responsivity. In particular, dye-conjugated upconverting nanoparticles (UCNPs) are among the most promising FRET-based sensor candidates. UCNPs have a multi-modal emission profile that allows for ratiometric sensing, and by conjugating a biosensitive dye to their surface, this profile can be used to measure localized variations in biological parameters. However, the complex nature of the UCNP energy profile as well as reabsorption of emitted photons must be taken into account in order to properly sense the target parameters. To our knowledge, no proposed UCNP-based sensor has accurately taken care of these intricacies. In this article, we account for these complexities by creating a FRET-based sensor that measures pH. This sensor utilizes Thulium (

Identifiers

PMID38938524
PMCPMC11210210

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.