Evidence map›Paper›PMID 38938509›Full record

ArticleCHEST critical care2024

Progressive Encephalopathy With New Pulmonary Opacities in an Immunocompromised Host.

Marika Orlov, Andrew T Pham, Dan Merrick, Markus Wu, Sias Scherger, Tanya Marvi, Arun Kannappan

Abstract read
In one paragraph

Article in CHEST critical care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marika OrlovDepartment of Pulmonary Sciences and Critical Care Medicine (M. O., T. M., and A. K.), the Department of Medicine (A. T. P.), the Department of Pathology (D. M.), the Department of Radiology (M. W.), University of Colorado Anschutz Medical Campus, Aurora, CO; and the Department of Infectious Diseases (S. S.), University of Nebraska Medical Center, Omaha, NE.
Andrew T PhamDepartment of Pulmonary Sciences and Critical Care Medicine (M. O., T. M., and A. K.), the Department of Medicine (A. T. P.), the Department of Pathology (D. M.), the Department of Radiology (M. W.), University of Colorado Anschutz Medical Campus, Aurora, CO; and the Department of Infectious Diseases (S. S.), University of Nebraska Medical Center, Omaha, NE.
Dan MerrickDepartment of Pulmonary Sciences and Critical Care Medicine (M. O., T. M., and A. K.), the Department of Medicine (A. T. P.), the Department of Pathology (D. M.), the Department of Radiology (M. W.), University of Colorado Anschutz Medical Campus, Aurora, CO; and the Department of Infectious Diseases (S. S.), University of Nebraska Medical Center, Omaha, NE.
Markus WuDepartment of Pulmonary Sciences and Critical Care Medicine (M. O., T. M., and A. K.), the Department of Medicine (A. T. P.), the Department of Pathology (D. M.), the Department of Radiology (M. W.), University of Colorado Anschutz Medical Campus, Aurora, CO; and the Department of Infectious Diseases (S. S.), University of Nebraska Medical Center, Omaha, NE.
Sias SchergerDepartment of Pulmonary Sciences and Critical Care Medicine (M. O., T. M., and A. K.), the Department of Medicine (A. T. P.), the Department of Pathology (D. M.), the Department of Radiology (M. W.), University of Colorado Anschutz Medical Campus, Aurora, CO; and the Department of Infectious Diseases (S. S.), University of Nebraska Medical Center, Omaha, NE.
Tanya MarviDepartment of Pulmonary Sciences and Critical Care Medicine (M. O., T. M., and A. K.), the Department of Medicine (A. T. P.), the Department of Pathology (D. M.), the Department of Radiology (M. W.), University of Colorado Anschutz Medical Campus, Aurora, CO; and the Department of Infectious Diseases (S. S.), University of Nebraska Medical Center, Omaha, NE.
Arun KannappanDepartment of Pulmonary Sciences and Critical Care Medicine (M. O., T. M., and A. K.), the Department of Medicine (A. T. P.), the Department of Pathology (D. M.), the Department of Radiology (M. W.), University of Colorado Anschutz Medical Campus, Aurora, CO; and the Department of Infectious Diseases (S. S.), University of Nebraska Medical Center, Omaha, NE.

Funding

MULTIDISCIPLINARY RESPIRATORY DISEASES RESEARCH TRAININGT32HL007085 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ELLEN L BURNHAM, LISA A MAIER · 1985 to 2026
$21.6M
NHLBI NIH HHS T32 HL007085
6 · The paper itself

Abstract

A 48-year-old man with history of recent travel to central Mexico and immunosuppression sought treatment with a 1-month-long history of progressive headache, fatigue, word-finding difficulties, and night sweats. The patient had a history of end-stage renal disease; he had undergone a kidney transplantation 7 years prior with good graft function with immunosuppression with tacrolimus, everolimus, and low-dose prednisone. At an outside hospital, he recently had been treated with empiric antibiotics for meningitis, but these were discontinued given the low suspicion for a bacterial cause. After discharge, he continued to have headaches, limited oral intake, persistent nausea, urinary frequency, and falls, prompting him to seek treatment at the ED. Physical examination findings were benign aside from disorientation. Laboratory workup was significant for hyponatremia of 122 mM, creatinine of 1.4 mg/dL (baseline, 1.4-1.5 mg/dL), WBC count of 7.2 10

Identifiers

PMID38938509
PMCPMC11210216

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.