Evidence map›Paper›PMID 38938424›Full record

ArticleOpen veterinary journal2024

Antidiabetic, antidyslipidemia, and renoprotector potency of butterfly pea flower extract (

Wahyu Widowati, Lusiana Darsono, Maria R Natariza, Novaldo W Waluyo, Abigail M Gleyriena Tenda, Berlian H Siahaan, Reza Oktaviani, Fadhilah Haifa Zahiroh, Herry S Utomo, Rizal Rizal

Abstract read
In one paragraph

Article in Open veterinary journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Plants (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wahyu WidowatiFaculty of Medicine, Maranatha Christian University, Bandung, West Java 40164, Indonesia.
Lusiana DarsonoFaculty of Medicine, Maranatha Christian University, Bandung, West Java 40164, Indonesia.
Maria R NatarizaFaculty of Medicine, Maranatha Christian University, Bandung, West Java 40164, Indonesia.
Novaldo W WaluyoFaculty of Medicine, Maranatha Christian University, Bandung, West Java 40164, Indonesia.
Abigail M Gleyriena TendaFaculty of Medicine, Maranatha Christian University, Bandung, West Java 40164, Indonesia.
Berlian H SiahaanFaculty of Medicine, Maranatha Christian University, Bandung, West Java 40164, Indonesia.
Reza OktavianiFaculty of Medicine, Maranatha Christian University, Bandung, West Java 40164, Indonesia.
Fadhilah Haifa ZahirohAretha Medika Utama Biomolecular and Biomedical Research Center, Bandung, West Java 40163, Indonesia.
Herry S UtomoLouisiana State University (LSU) AgCenter, H. Rouse Caffey Rice Research Station, Rayne, LA 70578, USA.
Rizal RizalAretha Medika Utama Biomolecular and Biomedical Research Center, Bandung, West Java 40163, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diabetes mellitus (DM) is a long-term condition marked by high blood glucose levels caused by insulin resistance which will lead to complications of other diseases such as dyslipidemia, which also affects the health of the liver and kidneys. Butterfly pea flower ( Aim: The purpose of this study is to examine the potential of butterfly pea flower extract (BPE) as an antidiabetic, anti-dyslipidemia, and renoprotection. Methods: Results: Treatment of BPE 800 mg/kg BW increased levels of GSH-Px, GST, albumin, and serum protein. BPE decreased TNF-α, NF-kB, and ALP. BPE also decreased BUN, serum CR, and serum UA. Conclusion: BPE has the potential to be used as a drug alternative for the treatment of DM and dyslipidemia as well as a hepatoprotective and renoprotective agent.

Indexed as

Diabetes Mellitus, ExperimentalDyslipidemiasHypoglycemic AgentsHypolipidemic AgentsPlant ExtractsRats, Sprague-DawleyAnimalsFlowersMaleRatsHypoglycemic AgentsHypolipidemic AgentsPlant ExtractsAntidiabeticClitorea ternatea L.Diabetes mellitusDyslipidemiaRenoprotective

Identifiers

PMID38938424
PMCPMC11199744

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.