Evidence map›Paper›PMID 38938378›Full record

ArticleFrontiers in medicine2024

Investigating the role of Caspase-1 in a mouse model of Juvenile X-linked Retinoschisis.

Ella J Gehrke, Araniko Pandey, Jacob Thompson, Sajag Bhattarai, Prajwal Gurung, Ying Hsu, Arlene V Drack

Abstract read
In one paragraph

Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ella J Gehrke *Department of Ophthalmology and Visual Sciences, IVR, University of Iowa, Iowa City, IA, United States.
Araniko Pandey *Department of Ophthalmology and Visual Sciences, IVR, University of Iowa, Iowa City, IA, United States.
Jacob ThompsonDepartment of Ophthalmology and Visual Sciences, IVR, University of Iowa, Iowa City, IA, United States.
Sajag BhattaraiDepartment of Ophthalmology and Visual Sciences, IVR, University of Iowa, Iowa City, IA, United States.
Prajwal GurungDivision of Infectious Diseases, Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, United States.
Ying HsuDepartment of Ophthalmology and Visual Sciences, IVR, University of Iowa, Iowa City, IA, United States.
Arlene V DrackDepartment of Ophthalmology and Visual Sciences, IVR, University of Iowa, Iowa City, IA, United States.

Funding

Stem Cell and Organoid CoreP30EY025580 · NEI · UNIVERSITY OF IOWA · PI Budd A Tucker · 2016 to 2026
$6.9M
Implicating a previously unknown Dectin1-RIPK2-CARD9 signaling in providing resistance against Leishmania major infectionR01AI155425 · NIAID · UNIVERSITY OF IOWA · PI GURUNG, PRAJWAL · 2021 to 2025
$2.5M
NEI NIH HHS P30 EY025580NIAID NIH HHS R01 AI155425
6 · The paper itself

Abstract

Purpose: Previous studies have reported Caspase-1 ( Methods: Results: Intraretinal schisis was not observed on OCT in WT eyes, while schisis was apparent in most Conclusion: Although

Indexed as

apoptosisCaspase-1disease mechanismselectroretinogramimmunologyretinoschisinX-linked Retinoschisis

Identifiers

PMID38938378
PMCPMC11208328

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.