Evidence map›Paper›PMID 38938374›Full record

ArticleJournal of extracellular biology2023

Extracellular vesicle-mediated protein delivery to the liver.

Nazma F Ilahibaks, Marieke T Roefs, Maike A D Brans, Christian Snijders Blok, Saskia C A de Jager, Raymond M Schiffelers, Pieter Vader, Zhiyong Lei, Joost P G Sluijter

Erratum issuedAbstract read
In one paragraph

Article in Journal of extracellular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Nazma F IlahibaksLaboratory of Experimental Cardiology, Department Heart & Lungs University Medical Center Utrecht Utrecht The Netherlands.ORCID https://orcid.org/0000-0002-4910-3305
Marieke T RoefsLaboratory of Experimental Cardiology, Department Heart & Lungs University Medical Center Utrecht Utrecht The Netherlands.ORCID https://orcid.org/0000-0002-6872-7092
Maike A D BransLaboratory of Experimental Cardiology, Department Heart & Lungs University Medical Center Utrecht Utrecht The Netherlands.
Christian Snijders BlokLaboratory of Experimental Cardiology, Department Heart & Lungs University Medical Center Utrecht Utrecht The Netherlands.
Saskia C A de JagerLaboratory of Experimental Cardiology, Department Heart & Lungs University Medical Center Utrecht Utrecht The Netherlands.ORCID https://orcid.org/0000-0002-5233-0066
Raymond M SchiffelersCDL Research University Medical Center Utrecht Utrecht The Netherlands.
Pieter VaderLaboratory of Experimental Cardiology, Department Heart & Lungs University Medical Center Utrecht Utrecht The Netherlands.ORCID https://orcid.org/0000-0002-7059-8920
Zhiyong LeiLaboratory of Experimental Cardiology, Department Heart & Lungs University Medical Center Utrecht Utrecht The Netherlands.
Joost P G SluijterLaboratory of Experimental Cardiology, Department Heart & Lungs University Medical Center Utrecht Utrecht The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) are nanoscale particles that facilitate intercellular communication. They are regarded as a promising natural drug delivery system for transporting and delivering bioactive macromolecules to target cells. Recently, researchers have engineered EVs with FKBP12/FRB heterodimerization domains that interact with rapamycin to load and deliver exogenous proteins for both

Indexed as

drug deliveryEV‐mediated drug deliveryEV uptakeexosomesextracellular vesiclesmicrovesiclesprotein delivery

Identifiers

PMID38938374
PMCPMC11080727

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.