Evidence map›Paper›PMID 38937455›Full record

ArticleNature communications2024

Implicating the red body of Nannochloropsis in forming the recalcitrant cell wall polymer algaenan.

Christopher W Gee, Johan Andersen-Ranberg, Ethan Boynton, Rachel Z Rosen, Danielle Jorgens, Patricia Grob, Hoi-Ying N Holman, Krishna K Niyogi

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Marine drugs · 2025
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christopher W GeeHoward Hughes Medical Institute, University of California, Berkeley, CA, 94720, USA.ORCID 0000-0001-7667-398X
Johan Andersen-RanbergUniversity of Copenhagen, Department of Plant and Environmental Sciences, Frederiksberg, DK-1871, Denmark.ORCID 0000-0002-6597-3431
Ethan BoyntonHoward Hughes Medical Institute, University of California, Berkeley, CA, 94720, USA.ORCID 0009-0000-2148-0857
Rachel Z RosenDepartment of Chemistry, University of California, Berkeley, CA, 94702, USA.
Danielle JorgensElectron Microscope Laboratory, University of California, Berkeley, CA, 94720, USA.
Patricia GrobHoward Hughes Medical Institute, University of California, Berkeley, CA, 94720, USA.ORCID 0000-0002-8330-8961
Hoi-Ying N HolmanElectron Microscope Laboratory, University of California, Berkeley, CA, 94720, USA.ORCID 0000-0002-7534-2625
Krishna K NiyogiHoward Hughes Medical Institute, University of California, Berkeley, CA, 94720, USA. niyogi@berkeley.edu.ORCID 0000-0001-7229-2071

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stramenopile algae contribute significantly to global primary productivity, and one class, Eustigmatophyceae, is increasingly studied for applications in high-value lipid production. Yet much about their basic biology remains unknown, including the nature of an enigmatic, pigmented globule found in vegetative cells. Here, we present an in-depth examination of this "red body," focusing on Nannochloropsis oceanica. During the cell cycle, the red body forms adjacent to the plastid, but unexpectedly it is secreted and released with the autosporangial wall following cell division. Shed red bodies contain antioxidant ketocarotenoids, and overexpression of a beta-carotene ketolase results in enlarged red bodies. Infrared spectroscopy indicates long-chain, aliphatic lipids in shed red bodies and cell walls, and UHPLC-HRMS detects a C32 alkyl diol, a potential precursor of algaenan, a recalcitrant cell wall polymer. We propose that the red body transports algaenan precursors from plastid to apoplast to be incorporated into daughter cell walls.

Indexed as

Cell WallPlastidsStramenopiles

Identifiers

PMID38937455
PMCPMC11211512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.