Evidence map›Paper›PMID 38937296›Full record

ArticleJournal of molecular modeling2024

Specific interaction from different Aβ

Xvzhi Gao, Yvning Guan, Chuanbo Wang, Mengke Jia, Sajjad Ahmad, Muhammad Fahad Nouman, Hongqi Ai

Abstract read
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In one paragraph

Article in Journal of molecular modeling, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xvzhi GaoSchool of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, People's Republic of China.
Yvning GuanSchool of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, People's Republic of China.
Chuanbo WangSchool of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, People's Republic of China.
Mengke JiaSchool of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, People's Republic of China.
Sajjad AhmadSchool of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, People's Republic of China.
Muhammad Fahad NoumanSchool of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, People's Republic of China.
Hongqi AiSchool of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, People's Republic of China. chm_aihq@ujn.edu.cn.

Funding

Shandong Provincial Natural Science Foundation of China ZR2022MB073
6 · The paper itself

Abstract

contextExisting researches confirmed that β amyloid (Aβ) has a high affinity for the α7 nicotinic acetylcholine receptor (α7nAChR), associating closely to Alzheimer's disease. The majority of related studies focused on the experimental reports on the neuroprotective role of Aβ fragment (Aβ

methodsThe protein-ligand docking server of CABS-DOCK was employed to obtain the α7nAChR-Aβ

Indexed as

alpha7 Nicotinic Acetylcholine ReceptorAmyloid beta-PeptidesMolecular Docking SimulationMolecular Dynamics SimulationPeptide FragmentsProtein BindingBinding SitesHumansLigandsalpha7 Nicotinic Acetylcholine ReceptorAmyloid beta-Peptidesamyloid beta-protein (1-42)LigandsPeptide FragmentsADAβx fragmentsBinding sitesKey residuesα7nAChR receptor

Identifiers

PMID38937296

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.