Evidence map›Paper›PMID 38936294›Full record

ArticleUltrasonics sonochemistry2024

Ultrasonic-assisted extraction of a low molecular weight polysaccharide from Nostoc commune Vaucher and its structural characterization and immunomodulatory activity.

Ying Pan, Chunjuan Liu, Shuo Jiang, Lili Guan, Xinyao Liu, Liankui Wen

Abstract read
In one paragraph

Article in Ultrasonics sonochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Structural Analysis of an Inulin-Type Fructan fromMolecules (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Foods (Basel, Switzerland) · 2026
    Article
  4. Synergistic Polyphenol Recovery FromJournal of analytical methods in chemistry · 2026
    Article
  5. Article
  6. Article
  7. Ultrasound-assisted HFrontiers in pharmacology · 2025
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ying PanCollege of Food Science and Engineering, Jilin Agricultural University, Changchun 130118, PR China; Jilin Province Economic Management Cadre College,Changchun 130012, PR China.
Chunjuan LiuJilin Province Economic Management Cadre College,Changchun 130012, PR China.
Shuo JiangCollege of Food Science and Engineering, Jilin Agricultural University, Changchun 130118, PR China.
Lili GuanCollege of Life Sciences, Jilin Agricultural University, Changchun 130118, PR China.
Xinyao LiuCollege of Food Science and Engineering, Jilin Agricultural University, Changchun 130118, PR China. Electronic address: liuxinyao6660@163.com.
Liankui WenCollege of Food Science and Engineering, Jilin Agricultural University, Changchun 130118, PR China. Electronic address: wenliankui@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the current study, a novel crude polysaccharide (cNCEP) was extracted from N. commune Vaucher utilizing ultrasonic-assisted extraction (UAE) with 60 % ethanol, employing response surface methodology. The optimal yield of cNCEP was determined to be 8.07 ± 0.08 mg/g, achieved through ultrasonic-assisted extraction under the conditions of a material-to-liquid ratio of 1:22, temperature of 56 °C, power of 570 W, and duration of 147 min. Subsequent purification of NCEP via Sephadex G75 resulted in a novel polysaccharide with a molecular weight of 20.466 kDa. NCEP exhibited significant scavenging activites against DPPH and hydroxyl radicals, as well as notable in vitro immunomodulatory properties. Furthermore, the mechanisms underlying the immunomodulatory effects of NCEP, involving enhancement of immunity, were investigated, revealing potential regulation of MAPK and TLR4-IRF7-NF-κB signaling pathways through RNA-Seq and Western blot analyses. These findings highlight the promising potential of NCEP as an organic immunomodulatory agent and functional food ingredient.

Indexed as

Immunologic FactorsMolecular WeightNostoc communeUltrasonic WavesAnimalsChemical FractionationMicePolysaccharidesRAW 264.7 CellsSignal TransductionImmunologic FactorsPolysaccharidesImmunomodulatory activityNostoc commune VaucherPolysaccharideUltrasonic-assisted extraction

Identifiers

PMID38936294
PMCPMC11260389

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.