Evidence map›Paper›PMID 38936182›Full record

ArticleDrug and alcohol dependence2024

Hair cortisol and substance use among women currently experiencing intimate partner violence: The role of PTSD symptom severity.

Shannon R Forkus, Silvi C Goldstein, Melissa R Schick, Julianne C Flanagan, Nicole H Weiss

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shannon R ForkusDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA. Electronic address: Forkus@musc.edu.
Silvi C GoldsteinDepartment of Psychology, University of Rhode Island, Kingston, RI, USA.
Melissa R SchickDepartment of Psychiatry, Yale University, New Haven, CT, USA.
Julianne C FlanaganDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA; Ralph H. Johnson VA Medical Center, Charleston, SC, USA.
Nicole H WeissDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Project 4: Neonatal Abstinence Syndrome (NAS): Fetus to First YearsP20GM125507 · NIGMS · RHODE ISLAND HOSPITAL · PI JOSIAH D RICH · 2018 to 2026
$23.4M
Research Training Program in Substance Use PreventionT32DA019426 · NIDA · YALE UNIVERSITY · PI TAMI P SULLIVAN · 2005 to 2026
$7.5M
PTSD, Negative and Positive Emotion Dysfunction and Substance USE in IPV VictimsK23DA039327 · NIDA · YALE UNIVERSITY · PI WEISS, NICOLE HOLLAND · 2016 to 2020
$756k
The effect of self-compassion on integrated treatment outcomes among veterans with co-occurring AUD and PTSD.F32AA031161 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI FORKUS, SHANNON · 2023 to 2024
$148k
Race and sex as moderators of harm reduction pharmacobehavioral treatment outcomes for alcohol use disorder among people experiencing homelessnessF31AA029274 · NIAAA · UNIVERSITY OF RHODE ISLAND · PI GOLDSTEIN, SILVI CARA · 2021 to 2022
$77k
NCATS NIH HHS UL1 TR001863NIAAA NIH HHS F31 AA029274NIAAA NIH HHS F32 AA031161NIDA NIH HHS K23 DA039327NIDA NIH HHS T32 DA019426NIGMS NIH HHS P20 GM125507
6 · The paper itself

Abstract

introductionSubstance use is highly prevalent among women experiencing intimate partner violence (IPV) and has been associated with dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis and resulting cortisol response. Posttraumatic stress disorder (PTSD) symptoms may play an important role in exacerbating the association between cortisol levels and substance use behaviors. PURPOSE: This study examined the role of PTSD symptoms in the relation between cortisol and past month substance use behaviors. The current study used hair cortisol as an index of past 30-day HPA-axis functioning and ecological momentary assessment (EMA) to characterize substance use behaviors more accurately over a 30-day period.

methodParticipants were 90 community women who had experienced physical or sexual IPV in the past 30 days by their current male partner and used any amount of alcohol or drugs (M age = 40.71; 54.4 % white). Participants completed (a) a baseline interview, (b) EMA for 30-days, and (c) a follow up interview where they were asked to provide a hair sample for cortisol analyses. Data collection took place from 2018 to 2020.

resultsPTSD severity moderated the relations between cortisol and days of drinking and binge drinking. In the context of high PTSD symptomology, women with high cortisol levels spent, on average, an additional 7.4 days drinking and 8.1 days binge drinking in the past 30 days compared to women with low cortisol levels, in a model adjusted for age.

conclusionsResults highlight the prominent role of PTSD symptoms in the association between cortisol and alcohol use among women experiencing IPV.

Indexed as

HairHydrocortisoneIntimate Partner ViolenceStress Disorders, Post-TraumaticSubstance-Related DisordersAdultEcological Momentary AssessmentFemaleHumansMiddle AgedSeverity of Illness IndexHydrocortisoneHair cortisolHPA-axis functioningIntimate partner violencePTSDSubstance use

Identifiers

PMID38936182
PMCPMC11439414

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.