Evidence map›Paper›PMID 38935948›Full record

ArticleJMIR bioinformatics and biotechnology2022

Monitoring Risk Factors and Improving Adherence to Therapy in Patients With Chronic Kidney Disease (Smit-CKD Project): Pilot Observational Study.

Antonio Vilasi, Vincenzo Antonio Panuccio, Salvatore Morante, Antonino Villa, Maria Carmela Versace, Sabrina Mezzatesta, Sergio Mercuri, Rosalinda Inguanta, Giuseppe Aiello, Demetrio Cutrupi and 5 more

Abstract read
In one paragraph

Article in JMIR bioinformatics and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Antonio VilasiInstitute of Clinical Physiology, National Research Council, Reggio Calabria, Italy.ORCID https://orcid.org/0000-0002-9393-2418
Vincenzo Antonio PanuccioNephrology Unit, Grande Ospedale Metropolitano Bianchi Melacrino Morelli, Reggio Calabria, Italy.ORCID https://orcid.org/0000-0001-7819-7518
Salvatore MoranteImmedia Società per Azioni, Reggio Calabria, Italy.ORCID https://orcid.org/0000-0002-1453-130X
Antonino VillaImmedia Società per Azioni, Reggio Calabria, Italy.ORCID https://orcid.org/0000-0003-3936-5114
Maria Carmela VersaceInstitute of Clinical Physiology, National Research Council, Reggio Calabria, Italy.ORCID https://orcid.org/0000-0003-3402-0117
Sabrina MezzatestaInstitute of Clinical Physiology, National Research Council, Reggio Calabria, Italy.ORCID https://orcid.org/0000-0002-2896-9636
Sergio MercuriMercuri Informatica, Reggio Calabria, Italy.ORCID https://orcid.org/0000-0002-2171-1210
Rosalinda InguantaDepartment of Engineering, University of Palermo, Palermo, Italy.ORCID https://orcid.org/0000-0001-8166-7998
Giuseppe AielloDepartment of Engineering, University of Palermo, Palermo, Italy.ORCID https://orcid.org/0000-0001-6362-8952
Demetrio CutrupiInstitute of Clinical Physiology, National Research Council, Reggio Calabria, Italy.ORCID https://orcid.org/0000-0002-0136-1161
Rossella PuglisiImmedia Società per Azioni, Reggio Calabria, Italy.ORCID https://orcid.org/0000-0002-3580-9104
Salvatore CapriaInstitute of Clinical Physiology, National Research Council, Reggio Calabria, Italy.ORCID https://orcid.org/0000-0002-5222-1724
Maurizio Li VigniImmedia Società per Azioni, Reggio Calabria, Italy.ORCID https://orcid.org/0000-0002-1194-1477
Giovanni TripepiInstitute of Clinical Physiology, National Research Council, Reggio Calabria, Italy.ORCID https://orcid.org/0000-0002-3580-4602
Claudia TorinoInstitute of Clinical Physiology, National Research Council, Reggio Calabria, Italy.ORCID https://orcid.org/0000-0002-4967-0916

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease is a major public health issue, with about 13% of the general adult population and 30% of the elderly affected. Patients in the last stage of this disease have an almost uniquely high risk of death and cardiovascular events, with reduced adherence to therapy representing an additional risk factor for cardiovascular morbidity and mortality. Considering the increased penetration of mobile phones, a mobile app could educate patients to autonomously monitor cardiorenal risk factors.

objectiveWith this background in mind, we developed an integrated system of a server and app with the aim of improving self-monitoring of cardiovascular and renal risk factors and adherence to therapy.

methodsThe software infrastructure for both the Smit-CKD server and Smit-CKD app was developed using standard web-oriented development methodologies preferring open source tools when available. To make the Smit-CKD app suitable for Android and iOS, platforms that allow the development of a multiplatform app starting from a single source code were used. The integrated system was field tested with the help of 22 participants. User satisfaction and adherence to therapy were measured by questionnaires specifically designed for this study; regular use of the app was measured using the daily reports available on the platform.

resultsThe Smit-CKD app allows the monitoring of cardiorenal risk factors, such as blood pressure, weight, and blood glucose. Collected data are transmitted in real time to the referring general practitioner. In addition, special reminders improve adherence to the medication regimen. Via the Smit-CKD server, general practitioners can monitor the clinical status of their patients and their adherence to therapy. During the test phase, 73% (16/22) of subjects entered all the required data regularly and sent feedback on drug intake. After 6 months of use, the percentage of regular intake of medications rose from 64% (14/22) to 82% (18/22). Analysis of the evaluation questionnaires showed that both the app and server components were well accepted by the users.

conclusionsOur study demonstrated that a simple mobile app, created to self-monitor modifiable cardiorenal risk factors and adherence to therapy, is well tolerated by patients affected by chronic kidney disease. Further studies are required to clarify if the use of this integrated system will have long-term effects on therapy adherence and if self-monitoring of risk factors will improve clinical outcomes in this population.

Indexed as

adherencecardiaccardiologycardiovascularchronic kidney diseaseCKDeHealthhealth appintegrated systemkidneymHealthmobile appmobile healthmonitoringrenalrisk factorSMIT-CKDtherapy adherence

Identifiers

PMID38935948
PMCPMC11135230

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.