Evidence map›Paper›PMID 38935267›Full record

ArticleJournal of medical toxicology : official journal of the American College of Medical Toxicology2024

From Patient Registry to Multi-Center Research Consortium: the Toxicology Investigators Consortium (ToxIC) Turns Fifteen.

Jeffrey Brent, Paul Wax, Rachel Culbreth, Sharan Campleman, Kim Aldy

Abstract read
In one paragraph

Article in Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Responsiveness of the 2024-2030 ACMT Research Agenda to New Funding Priorities and Research Environment.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2026
    Article
  2. The Toxicology Investigators Consortium 2024 Annual Report.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2026
    Article
  3. Patient Centered Outcomes Research in Medical Toxicology.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2025
    Review
  4. The Value of Medical Toxicologists.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2025
    Article
  5. 20 Years of JMT: The Vital Role of Journals to Explain Things to Others and Ourselves.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2024
    Article
  6. The Toxicology Investigators Consortium 2023 Annual Report.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jeffrey BrentSchool of Medicine, University of Colorado, Aurora, CO, USA. Jeffrey.Brent@cuanschutz.edu.
Paul WaxAmerican College of Medical Toxicology, Phoenix, AZ, USA.
Rachel CulbrethAmerican College of Medical Toxicology, Phoenix, AZ, USA.ORCID 0000-0002-5270-2608
Sharan CamplemanAmerican College of Medical Toxicology, Phoenix, AZ, USA.
Kim AldyAmerican College of Medical Toxicology, Phoenix, AZ, USA.

Funding

Predicting medical consequences of novel fentanyl analog overdose using the Toxicology Investigators Consortium (TOXIC) R01DA048009 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Alex Francis Manini · 2020 to 2026
$6.7M
American Academy of Addiction Psychiatry American Academy of Addiction PsychiatryBTG International BTG InternationalCDC HHS Centers for Disease Control and PreventionNIDA NIH HHS R01 DA048009U.S. Food and Drug Administration U.S. Food and Drug Administration
6 · The paper itself

Abstract

The Toxicology Investigators Consortium (ToxIC) was launched as a prospective multi-center registry of cases who receive medical toxicology consultations. Now, with over 100,000 cases, the Core Registry continues to address many medical toxicology research questions and has served as the foundation for multiple sub-registries, including the North American Snakebite Registry and the Medications for Opioid Use Disorder sub-registry. ToxIC also has evolved a portfolio of non-registry-based projects utilizing medical toxicology physician site principal investigators who enroll patients through emergency departments, irrespective of whether they received a medical toxicology consultation. These studies include the FDA-ACMT COVID-19 ToxIC Pharmacovigilance Project, which identifies adverse drug reactions related to the treatment of COVID-19, the Fentalog Study a toxico-surveillance study of suspected opioid overdose cases, the Drug Overdose Toxico-Surveillance Reporting Program which enrolls either suspected stimulant or opioid overdose cases, and the just being launched Real-World Examination of Naloxone for Drug Overdose Reversal project. Given ToxIC's experience in multi-center studies and its well-developed infrastructure, it is well-positioned to provide a nimble response on the part of the medical toxicology community to addressing evolving toxicological threats, drug and chemical toxicosurveillance, and other important medical toxicology priorities.

Indexed as

COVID-19RegistriesToxicologyDrug OverdoseHumansMulticenter Studies as TopicPharmacovigilanceUnited StatesEpidemiologyMedical ToxicologyOverdosePoisoningSurveillance

Identifiers

PMID38935267
PMCPMC11288211

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.