Evidence map›Paper›PMID 38935149›Full record

ArticlePediatric surgery international2024

Bowel function, urinary tract function, and health-related quality of life in males with anorectal malformations.

Joshua Gertler, Anna Löf Granström, Jenny Oddsberg, Anna Gunnarsdóttir, Anna Svenningsson, Tomas Wester, Lisa Örtqvist

Abstract read
In one paragraph

Article in Pediatric surgery international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joshua GertlerUnit of Pediatric Surgery, Karolinska University Hospital, Astrid Lindgrens Barnsjukhus Karolinska Universitetssjukhuset, Eugeniavägen C11:33, Solna, 17176, Stockholm, Sweden. joshua.gertler@ki.se.
Anna Löf GranströmUnit of Pediatric Surgery, Karolinska University Hospital, Astrid Lindgrens Barnsjukhus Karolinska Universitetssjukhuset, Eugeniavägen C11:33, Solna, 17176, Stockholm, Sweden.
Jenny OddsbergUnit of Pediatric Surgery, Karolinska University Hospital, Astrid Lindgrens Barnsjukhus Karolinska Universitetssjukhuset, Eugeniavägen C11:33, Solna, 17176, Stockholm, Sweden.
Anna GunnarsdóttirUnit of Pediatric Surgery, Karolinska University Hospital, Astrid Lindgrens Barnsjukhus Karolinska Universitetssjukhuset, Eugeniavägen C11:33, Solna, 17176, Stockholm, Sweden.
Anna SvenningssonUnit of Pediatric Surgery, Karolinska University Hospital, Astrid Lindgrens Barnsjukhus Karolinska Universitetssjukhuset, Eugeniavägen C11:33, Solna, 17176, Stockholm, Sweden.
Tomas WesterUnit of Pediatric Surgery, Karolinska University Hospital, Astrid Lindgrens Barnsjukhus Karolinska Universitetssjukhuset, Eugeniavägen C11:33, Solna, 17176, Stockholm, Sweden.
Lisa ÖrtqvistUnit of Pediatric Surgery, Karolinska University Hospital, Astrid Lindgrens Barnsjukhus Karolinska Universitetssjukhuset, Eugeniavägen C11:33, Solna, 17176, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere is a knowledge gap regarding long-term outcomes for males undergoing surgery for an anorectal malformation (ARM). The purpose of this study was to investigate bowel function, bladder function, and health-related quality of life (HRQoL) in male patients with an anorectal malformation.

methodsThis cross-sectional questionnaire-based study included males treated for ARM at our institution between 1994 and 2017. Bowel function was assessed with bowel function score (BFS) while urinary tract function was assessed with lower urinary tract symptoms (LUTS) questionnaires. Health-related quality of life (HRQoL) was investigated using age-relevant questionnaires (KIDSCREEN and PGWBI). Patient characteristics were retrospectively collected from the medical records and descriptive statistics were used for analysis. Functional outcomes were compared with gender and age-matched controls while HRQoL was compared to normative data. The study was approved by ethics review authorities.

resultsA total of 58 (44.6%) of 130 males responded to the questionnaires. Regarding bowel function, 24 (42.1%) of 57 patients and 81 (95.3%) of 85 controls, respectively, reported a well-preserved bowel function represented by a BFS ≥ 17 (p < 0.001). Soiling issues and 'feels urge' items improved significantly with age. In a linear regression model, BFS increased significantly with age. For most parameters, the proportion of ARM patients with lower urinary tract symptoms was larger, though not significantly, compared to the controls. However, straining and stress incontinence were reported significantly more often by ARM patients. In patients and controls, voiding outcomes in terms of prevalence of having symptoms and the number of cumulative symptoms drop with increasing age. Children and adults reported similar or, in some domains, better HRQoL outcomes when compared to normative European data.

conclusionBowel function is impaired in male patients with ARM but significantly improves with age. Urinary tract function was affected, but overall comparable to the controls. HRQoL was unaffected. No significant association between the studied outcomes could be shown. LEVEL OF EVIDENCE: III.

Indexed as

Anorectal MalformationsQuality of LifeAdolescentAdultChildChild, PreschoolCross-Sectional StudiesHumansLower Urinary Tract SymptomsMaleRetrospective StudiesSurveys and QuestionnairesYoung AdultAdulthoodAnorectal malformationBowel functionQoLSurgeryUrinary tract function

Identifiers

PMID38935149
PMCPMC11211194

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.