ArticleEuropean radiology2024
Synthetic hematocrit from virtual non-contrast images for myocardial extracellular volume evaluation with photon-counting detector CT.
Article in European radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- CT-derived myocardial extracellular volume: current evidence, clinical utility, and the emerging role of photon-counting CT-a systematic review.European radiology experimental · 2026Pooled it
- Extracellular volume fraction by cardiac computed tomography (ECVEuropean heart journal. Imaging methods and practice · 2026Review
- ESR Innovation in Focus: photon-counting detector CT.European radiology · 2026Article
- Advanced myocardial characterization and function with cardiac CT.The international journal of cardiovascular imaging · 2026Review
- Demographically informed models for improving synthetic haematocrit and extracellular volume estimation in cardiac computed tomography.European heart journal. Imaging methods and practice · 2026Article
- Spectral Imaging Techniques in Heart Disease Assessment Using Photon-Counting Detector Computed Tomography.Echocardiography (Mount Kisco, N.Y.) · 2025Review
- Multienergy cardiovascular CT imaging: current state and future.The British journal of radiology · 2025Review
- Improvement of Quantification of Myocardial Synthetic ECV with Second-Generation Deep Learning Reconstruction.Journal of cardiovascular development and disease · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo assess the accuracy of a synthetic hematocrit derived from virtual non-contrast (VNC) and virtual non-iodine images (VNI) for myocardial extracellular volume (ECV) computation with photon-counting detector computed tomography (PCD-CT). MATERIALS AND
methodsConsecutive patients undergoing PCD-CT including a coronary CT angiography (CCTA) and a late enhancement (LE) scan and having a blood hematocrit were retrospectively included. In the first 75 patients (derivation cohort), CCTA and LE scans were reconstructed as VNI at 60, 70, and 80 keV and as VNC with quantum iterative reconstruction (QIR) strengths 2, 3, and 4. Blood pool attenuation (BP
resultsIn the derivation cohort (49 men, mean age 79 ± 8 years), a correlation between BP
conclusionSynthetic hematocrit calculated from VNC images enables an accurate computation of myocardial ECV with PCD-CT. CLINICAL RELEVANCE STATEMENT: Virtual non-contrast images from cardiac late enhancement scans with photon-counting detector CT allow the calculation of a synthetic hematocrit, which enables accurate computation of myocardial extracellular volume. KEY POINTS: Blood hematocrit is mandatory for conventional myocardial extracellular volume computation. Synthetic hematocrit can be calculated from virtual non-iodine and non-contrast photon-counting detector CT images. Synthetic hematocrit from virtual non-contrast images enables computation of the myocardial extracellular volume.
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