Evidence map›Paper›PMID 38934862›Full record

ArticleJournal of the American Heart Association2024

Preoperative Malnutrition Increases Risk of In-Hospital Mortality, Major Infection, and Longer Intensive Care Unit Stay After Ventricular Septal Defect Closure.

Rachel E Wittenberg, Kimberlee Gauvreau, Christopher P Duggan, Xinwei Du, Do Giang, Kishore Jayanthi, Nestor Sandoval, Sivakumar Sivalingam, Xiaolei Zhao, Kathy J Jenkins

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rachel E WittenbergHarvard Medical School Boston MA USA.ORCID 0000-0002-0823-5635
Kimberlee GauvreauHarvard Medical School Boston MA USA.ORCID 0000-0002-2597-3226
Christopher P DugganHarvard Medical School Boston MA USA.ORCID 0000-0001-8083-8193
Xinwei DuShanghai Children's Medical Center Shanghai China.
Do GiangNhi Dong 1 Ho Chi Minh City Vietnam.ORCID 0000-0002-2170-9938
Kishore JayanthiStar Hospital Hyderabad India.ORCID 0000-0001-6899-0440
Nestor SandovalFundación Cardioinfantil y LaCardio Bogotá Colombia.ORCID 0000-0002-9020-0422
Sivakumar SivalingamInstitut Jantung Negara Kuala Lumpur Malaysia.ORCID 0000-0002-7913-8701
Xiaolei ZhaoTEDA International Cardiovascular Hospital Tianjin China.ORCID 0000-0002-5011-5485
Kathy J JenkinsHarvard Medical School Boston MA USA.ORCID 0000-0002-8702-988X

Funding

ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Elizabeth Austen Lawson, Takara Leah Stanley · 1994 to 2026
$31.6M
NIDDK NIH HHS P30 DK040561
6 · The paper itself

Abstract

backgroundHigh energy requirements and poor feeding can lead to growth failure in patients with ventricular septal defect (VSD), but effects of preoperative malnutrition on surgical outcomes are poorly understood, especially in low-resource settings. METHODS AND

resultsWe analyzed a cohort of children <5 years of age undergoing VSD closure at 60 global centers participating in the International Quality Improvement Collaborative for Congenital Heart Disease, 2015 to 2020. We calculated adjusted odds ratios (ORs) for in-hospital death and major infection and adjusted coefficients for duration of intensive care unit stay for 4 measures of malnutrition: severe wasting (weight-for-height

conclusionsMalnutrition was associated with mortality, infection, and longer intensive care unit stay in a global cohort of children undergoing VSD closure.

Indexed as

Heart Septal Defects, VentricularHospital MortalityLength of StayMalnutritionCardiac Surgical ProceduresChild, PreschoolFemaleHumansInfantIntensive Care UnitsMaleNutritional StatusPostoperative ComplicationsRetrospective StudiesRisk AssessmentRisk Factorscongenital heart diseaseglobal healthmalnutritionmortalityventricular septal defect

Identifiers

PMID38934862
PMCPMC11255684

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.