Evidence map›Paper›PMID 38934858›Full record

ArticleJournal of the American Heart Association2024

Long-Term Visit-to-Visit Blood Pressure Variability and Cognitive Decline Among Patients With Hypertension: A Pooled Analysis of 3 National Prospective Cohorts.

Guangjun Zheng, Biying Zhou, Zhenger Fang, Xia Chen, Mingliang Liu, Fudong He, Haofeng Zhang, Haidong Zhu, Yanbin Dong, Guang Hao

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Review
  3. Visit-to-visit systolic blood pressure variability, blood pressure treatment intensity, and cognitive decline.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Guangjun ZhengDepartment of Public Health and Preventive Medicine, School of Medicine Jinan University Guangzhou China.ORCID 0000-0003-3017-2172
Biying ZhouDepartment of Public Health and Preventive Medicine, School of Medicine Jinan University Guangzhou China.
Zhenger FangDepartment of Public Health and Preventive Medicine, School of Medicine Jinan University Guangzhou China.ORCID 0009-0003-9531-9734
Xia ChenDepartment of Public Health and Preventive Medicine, School of Medicine Jinan University Guangzhou China.
Mingliang LiuDepartment of Public Health and Preventive Medicine, School of Medicine Jinan University Guangzhou China.ORCID 0000-0002-5393-4195
Fudong HeSchool of Public Health Guangdong Pharmaceutical University Guangzhou China.ORCID 0009-0003-7544-0852
Haofeng ZhangSchool of Public Health Guangdong Pharmaceutical University Guangzhou China.ORCID 0009-0009-1763-2788
Haidong ZhuGeorgia Prevention Institute, Department of Medicine, Medical College of Georgia Augusta University Augusta GA USA.ORCID 0000-0002-8384-0464
Yanbin DongGeorgia Prevention Institute, Department of Medicine, Medical College of Georgia Augusta University Augusta GA USA.ORCID 0000-0001-7848-7160
Guang HaoSchool of Public Health Guangdong Pharmaceutical University Guangzhou China.ORCID 0000-0003-3780-0223

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA limited number of studies investigated the association between blood pressure variability (BPV) and cognitive impairment in patients with hypertension. This study aimed to identify the longitudinal association between BPV and cognitive decline and the role of blood pressure (BP) control in this association. METHODS AND

resultsParticipants with hypertension from the HRS (Health and Retirement Study), the ELSA (English Longitudinal Study of Ageing), and the CHARLS (China Health and Retirement Longitudinal Study) were included. Variation independent of the mean (VIM) was adopted to measure BPV. Cognitive function was measured by standard questionnaires, and a standardized

conclusionsHigh BPV was independently associated with a faster cognitive decline among patients with hypertension, even those with antihypertensive medications or well-controlled BP. Further studies are needed to confirm our results and determine whether reducing BPV can prevent or delay cognitive decline.

Indexed as

Blood PressureCognitive DysfunctionHypertensionAgedAntihypertensive AgentsBlood Pressure DeterminationChinaCognitionFemaleHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesRisk FactorsTime FactorsAntihypertensive Agentsblood pressure variabilitycognitive declinepooled analysis

Identifiers

PMID38934858
PMCPMC11255695

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.