Evidence map›Paper›PMID 38934801›Full record

ReviewThe Journal of infectious diseases2024

Incidence of RSV in Adults: A Comprehensive Review of Observational Studies and Critical Gaps in Information.

Benjamin Doty, Parinaz Ghaswalla, Rhonda L Bohn, Sonia K Stoszek, Catherine A Panozzo

Abstract readReview
In one paragraph

Review in The Journal of infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Hospitalisation trends of respiratory syncytial virus (RSV) infection in adults, six European countries, before and during COVID-19, 2016 to 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  11. Recognising RSV infection in adults: The role of recently-developed vaccines.African journal of thoracic and critical care medicine · 2025
    Article
  12. Burden of respiratory syncytial virus in older adults in Brazil: insights from national surveillance data for the 2022-2023 period.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Benjamin DotyBohn Epidemiology, LLC, Boston, Massachusetts, USA.
Parinaz GhaswallaModerna, Inc, Cambridge, Massachusetts, USA.
Rhonda L BohnBohn Epidemiology, LLC, Boston, Massachusetts, USA.
Sonia K StoszekModerna, Inc, Cambridge, Massachusetts, USA.
Catherine A PanozzoModerna, Inc, Cambridge, Massachusetts, USA.

Funding

Moderna, Inc
6 · The paper itself

Abstract

backgroundWe conducted a global comprehensive literature review of observational studies reporting respiratory syncytial virus (RSV) incidence in adults and determined current evidence gaps.

methodsPubMed and Embase were searched for English-language publications (2000-2022) and congress abstracts (2019-2021) reporting RSV incidence rates/cumulative incidence. Cross-sectional studies, case series, and other designs estimating only RSV frequency were excluded. The search included all geographic areas; data were extracted by age group and underlying condition where available.

resultsIn total, 528 potentially relevant records were identified, of which 37 primary studies were relevant to this review. Most evidence was from high-income regions. Approximately two-thirds of the studies reported RSV incidence in the hospital setting. Fifteen studies included or focused exclusively on RSV incidence in adult populations with underlying conditions. Studies varied in their measurement and presentation of incidence. RSV incidence estimates were highly variable within and between geographic regions. Overall, RSV incidence tended to increase with age and was highest in adults with underlying conditions.

conclusionsEstimates of RSV incidence are highly variable across populations and geographies. Further population-based studies with well-defined, consistent case definitions and surveillance strategies are needed for accurate and comparable estimates of RSV incidence, particularly in the geographic regions identified by the gap analysis.

Indexed as

Respiratory Syncytial Virus InfectionsAdultAgedAged, 80 and overHumansIncidenceMiddle AgedObservational Studies as TopicRespiratory Syncytial Virus, HumanYoung Adultadultsgap analysisincidenceliterature reviewRSV

Identifiers

PMID38934801
PMCPMC11646608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.