ArticleJournal of food and drug analysis2024
Fluorescent carbon nanodot-based rapid cell nucleus staining and application for diagnosis.
Article in Journal of food and drug analysis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Carbon dots and DNA: DNA binding mechanisms and their effect on the cell cycle arrest.Journal of advanced research · 2026Article
- Harnessing Maillard reaction byproducts for dual emissive carbon quantum dots: a tunable optical platform.RSC advances · 2025Article
- Recent advances in fluorescent gold nanocluster-based bioanalytical analysis and imaging in living cell.Bioanalysis · 2025Review
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Authors and funding
8 authors.
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Abstract
Cell nucleus status decides the activities of corresponding cells, making its rapid and effective staining important for revealing the actual condition of biological environment in life science and related fields. In this study, fast staining of cell nucleus is realized by fluorescent carbon nanodots (CDs). The staining mechanism is due to the positively charged CD surface-induced cell membrane penetration, which facilitates the CD-nucleus binding via electrostatic attraction. The size of cell nucleus is easily measured with fluorescence imaging technique. In addition, the CD-based cell nucleus stain is applied for discriminating the normal and cancer cells by determining the cell-to-nucleus ratio with fluorescence images.
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