Evidence map›Paper›PMID 38934615›Full record

ArticleApplied and environmental microbiology2024

Enhanced catabolism of glycine betaine and derivatives provides improved osmotic stress protection in

Eric L Bruger, Zachary T Hying, Deepanshu Singla, Nicole L Márquez Reyes, Shubham Kumar Pandey, Jagdish Suresh Patel, Jannell V Bazurto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Glycine betaine metabolism is enabled inApplied and environmental microbiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eric L Bruger *Department of Plant and Microbial Biology, University of Minnesota-Twin Cities, St. Paul, Minnesota, USA.ORCID 0000-0002-6369-4180
Zachary T Hying *Department of Plant and Microbial Biology, University of Minnesota-Twin Cities, St. Paul, Minnesota, USA.
Deepanshu SinglaDepartment of Plant and Microbial Biology, University of Minnesota-Twin Cities, St. Paul, Minnesota, USA.
Nicole L Márquez ReyesDepartment of Plant and Microbial Biology, University of Minnesota-Twin Cities, St. Paul, Minnesota, USA.
Shubham Kumar PandeyDepartment of Chemical and Biological Engineering, University of Idaho, Moscow, Idaho, USA.
Jagdish Suresh PatelDepartment of Chemical and Biological Engineering, University of Idaho, Moscow, Idaho, USA.
Jannell V BazurtoDepartment of Plant and Microbial Biology, University of Minnesota-Twin Cities, St. Paul, Minnesota, USA.ORCID 0000-0001-9012-2260

Funding

Sequence-structure-function relationships in human visual photopigmentsP20GM104420 · NIGMS · UNIVERSITY OF IDAHO · PI VAN LEUVEN, JAMES · 2015 to 2024
$22.9M
Formaldehyde homeostasis and damage repair in a bacterial formaldehyde specialistR35GM146904 · NIGMS · UNIVERSITY OF MINNESOTA · PI Jannell V. Bazurto · 2022 to 2026
$1.8M
NIGMS NIH HHS P20 GM104420NIGMS NIH HHS R35 GM146904
6 · The paper itself

Abstract

Integration of metabolites into the overall metabolic network of a cell requires careful coordination dependent upon the ultimate usage of the metabolite. Different stoichiometric needs, and thus pathway fluxes, must exist for compounds destined for diverse uses, such as carbon sources, nitrogen sources, or stress-protective agents. Herein, we expand upon our previous work that highlighted the nature of glycine betaine (GB) metabolism in Methylobacteria to examine the utilization of GB-derivative compounds dimethylglycine (DMG) and sarcosine into

Indexed as

BetaineOsmotic PressureSarcosineBacterial ProteinsCarbonMethylobacterium extorquensBacterial ProteinsBetaineCarbondimethylglycineSarcosinedimethylglycineexperimental evolutionglycine betainemetabolic homeostasisosmolytesosmotic stress

Identifiers

PMID38934615
PMCPMC11323934

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.