Evidence map›Paper›PMID 38934081›Full record

ArticleJournal of biophotonics2024

Virtual-point-based deconvolution for optical-resolution photoacoustic microscopy.

Rui Yao, Anthony DiSpirito, Hongje Jang, Colton Thomas McGarraugh, Van Tu Nguyen, Lingyan Shi, Junjie Yao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biophotonics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rui YaoDepartment of Biomedical Engineering, Duke University, Durham, North Carolina, USA.ORCID 0009-0000-3710-7387
Anthony DiSpiritoDepartment of Biomedical Engineering, Duke University, Durham, North Carolina, USA.
Hongje JangDepartment of Biomedical Engineering, University of California San Diego, La Jolla, California, USA.
Colton Thomas McGarraughDepartment of Biomedical Engineering, Duke University, Durham, North Carolina, USA.
Van Tu NguyenDepartment of Biomedical Engineering, Duke University, Durham, North Carolina, USA.
Lingyan ShiDepartment of Biomedical Engineering, University of California San Diego, La Jolla, California, USA.
Junjie YaoDepartment of Biomedical Engineering, Duke University, Durham, North Carolina, USA.

Funding

High-resolution High-speed Photoacoustic and Ultrasound Imaging of SmallVessel Functions in Ischemic StrokeR01NS111039 · NINDS · DUKE UNIVERSITY · PI YAO, JUNJIE · 2019 to 2023
$2.7M
High-throughput Imaging-integrated Vascular Model for Understanding Thromboembolism and Therapeutics ScreeningR01HL166522 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Junjie Yao, Y. Shrike Zhang · 2023 to 2026
$2.7M
Head-mounted Photoacoustic Imaging of Deep-brain Neural Activities in Freely Behaving AnimalsRF1NS115581 · NINDS · DUKE UNIVERSITY · PI VERKHUSHA, VLADISLAV, YAO, JUNJIE · 2020 to 2020
$2.0M
High-Throughput Volumetric Photoacoustic Imaging of Living Vascularized OrganoidsR01EB028143 · NIBIB · DUKE UNIVERSITY · PI YAO, JUNJIE · 2019 to 2022
$2.0M
3D real-time super-resolution cavitation mapping in laser lithotripsy of urinary stone diseaseR01DK139109 · NIDDK · DUKE UNIVERSITY · PI Michael E Lipkin, Junjie Yao · 2024 to 2026
$1.8M
Transcranial Photoacoustic Imaging Using a Virtual ArrayR21EB027981 · NIBIB · PENNSYLVANIA STATE UNIVERSITY, THE · PI JING, YUN · 2020 to 2020
$455k
Photoacoustic-imaging-guided intravascular sonothrombolysisR21EB027304 · NIBIB · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI JIANG, XIAONING, YAO, JUNJIE · 2019 to 2020
$411k
Chan Zuckerberg Initiative Grant 2020-226178Duke University Pratt Beyond the Horizon GrantEli Lilly Research Award ProgramNHLBI NIH HHS R01 HL166522NIBIB NIH HHS R01 EB028143NIBIB NIH HHS R21 EB027304NIBIB NIH HHS R21 EB027981NIDDK NIH HHS R01 DK139109NINDS NIH HHS R01 NS111039NINDS NIH HHS RF1 NS115581The United States National Science Foundation (NSF) CAREER 2144788United States National Institutes of Health (NIH) R01DK139109United States National Institutes of Health (NIH) R21EB027981
6 · The paper itself

Abstract

Optical-resolution photoacoustic microscopy (OR-PAM) has been increasingly utilized for in vivo imaging of biological tissues, offering structural, functional, and molecular information. In OR-PAM, it is often necessary to make a trade-off between imaging depth, lateral resolution, field of view, and imaging speed. To improve the lateral resolution without sacrificing other performance metrics, we developed a virtual-point-based deconvolution algorithm for OR-PAM (VP-PAM). VP-PAM has achieved a resolution improvement ranging from 43% to 62.5% on a single-line target. In addition, it has outperformed Richardson-Lucy deconvolution with 15 iterations in both structural similarity index and peak signal-to-noise ratio on an OR-PAM image of mouse brain vasculature. When applied to an in vivo glass frog image obtained by a deep-penetrating OR-PAM system with compromised lateral resolution, VP-PAM yielded enhanced resolution and contrast with better-resolved microvessels.

Indexed as

Image Processing, Computer-AssistedMicroscopyPhotoacoustic TechniquesAlgorithmsAnimalsBrainMiceMicrovesselsOptical PhenomenaSignal-To-Noise Ratiodeconvolutiongenetic algorithmphotoacoustic microscopy

Identifiers

PMID38934081
PMCPMC11330737

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.