Evidence map›Paper›PMID 38934027›Full record

ArticleKidney research and clinical practice2024

The effect of pharmacist-led medication therapy management in the multidisciplinary care of acute kidney injury survivors.

Ting Wang, Hao-Cheng Kang, Chien-Chih Wu, Tsung-Lin Wu, Chih-Fen Huang, Vin-Cent Wu

Abstract read
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Article in Kidney research and clinical practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ting WangDepartment of Pharmacy, National Taiwan University Hospital, Taipei, Taiwan.
Hao-Cheng KangDepartment of Pharmacy, National Taiwan University Hospital, Taipei, Taiwan.
Chien-Chih WuDepartment of Pharmacy, National Taiwan University Hospital, Taipei, Taiwan.
Tsung-Lin WuDivision of Nephrology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Chih-Fen HuangDepartment of Pharmacy, National Taiwan University Hospital, Taipei, Taiwan.
Vin-Cent WuDivision of Nephrology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Acute Disease Quality Initiative advocates multidisciplinary care for the survivors of acute kidney injury (AKI). The bundled care strategy recognizes the role of pharmacists. However, their specific contributions in this context remain underexplored.

methodsThis retrospective study examined the efficacy of pharmacist-led post-AKI pharmaceutical care in outpatient settings at a single center. Adults with recent AKI during hospitalization, maintaining an estimated glomerular filtration rate <45 mL/min/1.73 m2 postdischarge, were enrolled in a multidisciplinary team care program from March 2022 to January 2023, with a 6-month follow-up period. Pharmacist-delivered care adhered to international multidisciplinary consensus guidelines. Efficacy was evaluated by analyzing medication-related recommendations, medication adherence, nephrotoxic drug utilization, and renoprotective medication usage before and after the intervention.

resultsA total of 40 patients were referred to the pharmacist-managed clinic. Of these, 33 patients (mean age, 63 ± 15 years; 60.6% male) attended the clinic. Nineteen patients completed follow-up visits. The pharmacist provided 14 medication-related recommendations to relevant physicians, with 10 of these recommendations (71.4%) being accepted. There was a significant decrease in the use of modifiable nephrotoxic drugs (p = 0.03). However, no significant improvements were noted in medication adherence or the utilization of renoprotective medications.

conclusionOur study underscores the potential benefits of pharmacist-led post-AKI bundled care strategy in outpatient settings. We observed a significant reduction in the utilization of modifiable nephrotoxic drugs, indicating the effectiveness of pharmacist interventions in optimizing medication regimens to mitigate renal harm.

Indexed as

Acute kidney injuryMedication therapy managementPharmaceutical services

Identifiers

PMID38934027
PMCPMC11237329

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.