Evidence map›Paper›PMID 38933738›Full record

ArticleOpen forum infectious diseases2024

In Utero Exposure to Maternal SARS-CoV-2 Infection Is Associated With Higher Left Ventricular Mass in Toddlers.

Mollie W Ockene, Duraisamy Balaguru, Ingrid L Ma, Samuel C Russo, Allison K Arpante, Alexandra Clifford, Olyvia J Jasset, Joon H Kim, Mabel Toribio, Takara L Stanley and 3 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mollie W OckeneMetabolism Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0003-0600-6617
Duraisamy BalaguruPediatric Cardiology, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-4790-7879
Ingrid L MaMetabolism Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.
Samuel C RussoMetabolism Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.
Allison K ArpanteMetabolism Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.
Alexandra CliffordMetabolism Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.
Olyvia J JassetVincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Joon H KimVincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Mabel ToribioMetabolism Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-4153-5568
Takara L StanleyMetabolism Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-2336-2958
Lydia L ShookVincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Andrea G EdlowVincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Lindsay T FourmanMetabolism Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-8148-7858

Funding

The Harvard Clinical and Translational Science CenterUL1TR002541 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2018 to 2022
$93.0M
ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Elizabeth Austen Lawson, Takara Leah Stanley · 1994 to 2026
$31.6M
Sex Differences in Fetal Brain-Placental Immune Programming in Maternal ObesityR01HD100022 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI EDLOW, ANDREA GOLDBERG · 2019 to 2021
$2.0M
NCATS NIH HHS UL1 TR002541NICHD NIH HHS R01 HD100022NIDDK NIH HHS P30 DK040561
6 · The paper itself

Abstract

The intrauterine environment plays a critical role in shaping chronic disease risk over the life course. We prospectively evaluated cardiometabolic outcomes in toddlers born to mothers with versus without prenatal severe acute respiratory syndrome coronavirus 2 infection. Children with in utero severe acute respiratory syndrome coronavirus 2 exposure had higher left ventricular mass in association with altered maternal immunologic indices.

Indexed as

cardiometabolic diseaseCOVID-19developmental origins of diseasein uteroleft ventricular mass

Identifiers

PMID38933738
PMCPMC11204912

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.