Evidence map›Paper›PMID 38932798›Full record

ReviewJournal of diabetes and metabolic disorders2024

Association of serum omentin levels with microvascular complications of type 2 diabetes mellitus: a systematic review and meta-analysis.

Kimia Kazemzadeh, Maedeh Bayani, Reza Khademi, Seyedeh-Fatemeh Sadat-Madani, Adrina Habibzadeh, Mahsa Shirani, Hani Ghadri, Mohammad Abbasalizadeh, Erfan Izadi, Mahsa Rezaee and 6 more

Abstract readReview
In one paragraph

Review in Journal of diabetes and metabolic disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Kimia KazemzadehStudent Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Maedeh Bayani *School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Reza Khademi *School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Seyedeh-Fatemeh Sadat-MadaniSchool of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Adrina HabibzadehSchool of Medicine, Fasa University of Medical Sciences, Fasa, Iran.
Mahsa ShiraniSchool of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hani GhadriSchool of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Mohammad AbbasalizadehSchool of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Erfan IzadiSchool of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran.
Mahsa RezaeeSchool of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Arshia ShafieiSchool of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Alireza JoudakiSchool of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hassan AsadigandomaniSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Niloofar DeraviSchool of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Seyed Mohmmadmahdi MeybodiYoung Researchers and Elite Club, Tabriz Branch, Islamic Azad University, Tabriz, Iran.
Melika Arab BafraniStudent Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Type 2 diabetes mellitus (T2DM) is a chronic condition associated with various microvascular complications, including neuropathy, retinopathy, and nephropathy. Recent studies have suggested a potential association between serum omentin levels and the risk of developing microvascular complications in patients with T2DM. However, the existing evidence remains inconclusive. Therefore, we conducted a systematic review and meta-analysis to examine the association between serum omentin levels and microvascular complications in T2DM patients. Methods: A comprehensive search was conducted in PubMed, Scopus, and Google Scholar databases to retrieve relevant articles published up to May 2023. Observational studies investigating omentin levels association with microvascular complications in T2DM patients were included. Data was extracted and hence analyzed. Results: A total of seven cross-sectional articles met the inclusion criteria, with a total population of 1587 participants. The meta-analysis revealed a significant association between serum omentin levels and microvascular complications in patients with T2DM. Serum omentin levels were lower in patients with microvascular complications than in those without complications (Mean difference, 95% confidence interval: -1.31 [-2.50, -0.13], I2 = 99.62%). Conclusion: This systematic review and meta-analysis provides evidence supporting an association between serum omentin levels and microvascular complications in patients with T2DM. The findings suggest that Omentin may be lower in T2DM patients with microvascular complications. Further research is warranted to elucidate the underlying mechanisms and explore the clinical implications of these findings. Supplementary Information: The online version contains supplementary material available at 10.1007/s40200-023-01359-2.

Indexed as

MicrovascularNephropathyOmentinRetinopathyT2DM

Identifiers

PMID38932798
PMCPMC11196567

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.