Evidence map›Paper›PMID 38932622›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2025

Collateral ligament strain is linearly related to coronal lower limb alignment: A biomechanical study.

Christian Peez, Luise Maria Hägerich, Felix Ruhl, Matthias Klimek, Thorben Briese, Johannes Glasbrenner, Adrian Deichsel, Michael J Raschke, Christoph Kittl, Elmar Herbst

Abstract read
In one paragraph

Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Two-year follow-up of varus progression in young professional football players.BMC sports science, medicine & rehabilitation · 2026
    Article
  2. Article
  3. Article
  4. Collateral ligament strain is linearly related to coronal lower limb alignment: A biomechanical study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Christian PeezDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Münster, Münster, Germany.ORCID http://orcid.org/0000-0001-8055-289X
Luise Maria HägerichDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Münster, Münster, Germany.
Felix RuhlDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Münster, Münster, Germany.
Matthias KlimekDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Münster, Münster, Germany.
Thorben BrieseDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Münster, Münster, Germany.
Johannes GlasbrennerDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Münster, Münster, Germany.
Adrian DeichselDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Münster, Münster, Germany.
Michael J RaschkeDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Münster, Münster, Germany.
Christoph KittlDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Münster, Münster, Germany.
Elmar HerbstDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Münster, Münster, Germany.

Funding

Programme 'Innovative Medical Research' of the University of Muenster, Germany
6 · The paper itself

Abstract

purposeThe purpose of this study was to analyse the influence of coronal lower limb alignment on collateral ligament strain.

methodsTwelve fresh-frozen human cadaveric knees were used. Long-leg standing radiographs were obtained to assess lower limb alignment. Specimens were axially loaded in a custom-made kinematics rig with 200 and 400 N, and dynamic varus/valgus angulation was simulated in 0°, 30°, and 60° of knee flexion. The changes in varus/valgus angulation and strain within different fibre regions of the collateral ligaments were captured using a three-dimensional optical measuring system to examine the axis-dependent strain behaviour of the superficial medial collateral ligament (sMCL) and lateral collateral ligament (LCL) at intervals of 2°.

resultsThe LCL and sMCL were exposed to the highest strain values at full extension (p < 0.001). Regardless of flexion angle and extent of axial loading, the ligament strain showed a strong and linear association with varus (all Pearson's r ≥ 0.98; p < 0.001) and valgus angulation (all Pearson's r ≥ -0.97; p < 0.01). At full extension and 400 N of axial loading, the anterior and posterior LCL fibres exceeded 4% ligament strain at 3.9° and 4.0° of varus, while the sMCL showed corresponding strain values of more than 4% at a valgus angle of 6.8°, 5.4° and 4.9° for its anterior, middle and posterior fibres, respectively.

conclusionThe strain within the native LCL and sMCL was linearly related to coronal lower limb alignment. Strain levels associated with potential ultrastructural damages to the ligaments of more than 4% were observed at 4° of varus and about 5° of valgus malalignment, respectively. When reconstructing the collateral ligaments, an additional realigning osteotomy should be considered in cases of chronic instability with a coronal malalignment exceeding 4°-5° to protect the graft and potentially reduce failures. LEVEL OF EVIDENCE: There is no level of evidence as this study was an experimental laboratory study.

Indexed as

CadaverKnee JointAgedBiomechanical PhenomenaCollateral LigamentsFemaleHumansLower ExtremityMaleMedial Collateral Ligament, KneeMiddle AgedRange of Motion, ArticularStress, MechanicalWeight-Bearingcollateral ligament straincoronal lower limb alignmentindividualized collateral ligament reconstructionlateral collateral ligamentsuperficial medial collateral ligament

Identifiers

PMID38932622
PMCPMC11716353

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.