Evidence map›Paper›PMID 38932373›Full record

ArticleVaccines2024

Effect of Prior ChAdOx1 COVID-19 Immunisation on T-Cell Responses to ChAdOx1-HBV.

Charlotte Davis, Dave Singh, Katie Anderson, Antonella Vardeu, Jakub Kopycinski, Alice Bridges-Webb, Alice Trickett, Susanne O'Brien, Matthew Downs, Randip Kaur and 8 more

Abstract read
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The immunogenicity and safety of adenoviral-based vaccines.Current opinion in allergy and clinical immunology · 2026
    Review
  2. Developing the next-generation of adenoviral vector vaccines.Human vaccines & immunotherapeutics · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Charlotte DavisBarinthus Biotherapeutics, Harwell, Didcot OX11 0DF, UK.ORCID 0000-0002-2701-2226
Dave SinghMedicines Evaluation Unit Ltd., Manchester M23 9QZ, UK.
Katie AndersonBarinthus Biotherapeutics, Harwell, Didcot OX11 0DF, UK.ORCID 0000-0001-7910-8003
Antonella VardeuBarinthus Biotherapeutics, Harwell, Didcot OX11 0DF, UK.
Jakub KopycinskiBarinthus Biotherapeutics, Harwell, Didcot OX11 0DF, UK.
Alice Bridges-WebbBarinthus Biotherapeutics, Harwell, Didcot OX11 0DF, UK.
Alice TrickettBarinthus Biotherapeutics, Harwell, Didcot OX11 0DF, UK.
Susanne O'BrienBarinthus Biotherapeutics, Harwell, Didcot OX11 0DF, UK.
Matthew DownsBarinthus Biotherapeutics, Harwell, Didcot OX11 0DF, UK.ORCID 0000-0002-3623-8059
Randip KaurBarinthus Biotherapeutics, Harwell, Didcot OX11 0DF, UK.
Radka KolenovskaBarinthus Biotherapeutics, Harwell, Didcot OX11 0DF, UK.
Louise BusseyBarinthus Biotherapeutics, Harwell, Didcot OX11 0DF, UK.
Kathryn RutkowskiBarinthus Biotherapeutics, Harwell, Didcot OX11 0DF, UK.
Sarah SebastianBarinthus Biotherapeutics, Harwell, Didcot OX11 0DF, UK.
Tamsin CargillNuffield Department of Medicine, University of Oxford, Oxford OX1 2JD, UK.ORCID 0000-0002-2863-0835
Eleanor BarnesNuffield Department of Medicine, University of Oxford, Oxford OX1 2JD, UK.
Thomas G EvansBarinthus Biotherapeutics, Harwell, Didcot OX11 0DF, UK.
Paola CicconiCentre for Clinical Vaccinology and Tropical Medicine (CCVTM), University of Oxford, Oxford OX1 2JD, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are varying data concerning the effect of prior anti-vector immunity on the T-cell response induced by immunisation with an identical vectored vaccine containing a heterologous antigen insert. To determine whether prior exposure to ChAdOx1-SARS-CoV2 immunisation (Vaxzevria

Indexed as

hepatitis BT cellvaccineVaxzevria

Identifiers

PMID38932373
PMCPMC11209196

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.