Evidence map›Paper›PMID 38932367›Full record

ArticleVaccines2024

Evolution of the Antigenic Landscape in Children and Young Adults with COVID-19 and MIS-C.

Lorenza Bellusci, Gabrielle Grubbs, Shaimaa Sait, Katherine W Herbst, Juan C Salazar, Surender Khurana, The Connecticut Children's Covid Collaborative

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lorenza BellusciDivision of Viral Products, Center for Biologics Evaluation and Research (CBER), FDA, Silver Spring, MD 20871, USA.
Gabrielle GrubbsDivision of Viral Products, Center for Biologics Evaluation and Research (CBER), FDA, Silver Spring, MD 20871, USA.
Shaimaa SaitDivision of Viral Products, Center for Biologics Evaluation and Research (CBER), FDA, Silver Spring, MD 20871, USA.ORCID 0000-0003-3094-5729
Katherine W HerbstDivision of Pediatric Infectious Diseases, Connecticut Children's, Hartford, CT 06106, USA.
Juan C SalazarDivision of Pediatric Infectious Diseases, Connecticut Children's, Hartford, CT 06106, USA.ORCID 0000-0003-3881-546X
Surender KhuranaDivision of Viral Products, Center for Biologics Evaluation and Research (CBER), FDA, Silver Spring, MD 20871, USA.
The Connecticut Children's Covid Collaborative

Funding

Identifying biomarker signatures of prognostic value for Multisystem Inflammatory Syndrome in Children (MIS-C)R33HD105613 · NICHD · CONNECTICUT CHILDREN'S MEDICAL CENTER · PI LAWRENCE, DAVID A, LYNES, MICHAEL A · 2023 to 2023
$3.2M
Identifying biomarker signatures of prognostic value for Multisystem Inflammatory Syndrome in Children (MIS-C)R61HD105613 · NICHD · CONNECTICUT CHILDREN'S MEDICAL CENTER · PI LAWRENCE, DAVID A, LYNES, MICHAEL A · 2021 to 2022
$1.9M
Eunice Kennedy Shriver National Institute of Child Health and Human Development R33HD105613Eunice Kennedy Shriver National Institute of Child Health and Human Development R61HD105613NICHD NIH HHS R33 HD105613NICHD NIH HHS R61 HD105613United States Food and Drug Administration FDA Perinatal Health Center of Excellence (PHCE) grant #GCBER005United States Food and Drug Administration FDA's Medical Countermeasures Initiative (MCMi) grant #OCET 2023-0235
6 · The paper itself

Abstract

There is minimal knowledge regarding the durability of neutralization capacity and level of binding antibody generated against the highly transmissible circulating Omicron subvariants following SARS-CoV-2 infection in children with acute COVID-19 and those diagnosed with multisystem inflammatory syndrome in children (MIS-C) in the absence of vaccination. In this study, SARS-CoV-2 neutralization titers against the ancestral strain (WA1) and Omicron sublineages were evaluated in unvaccinated children admitted for COVID-19 (

Indexed as

childrenCOVID-19MIS-CSARS-CoV-2vaccination

Identifiers

PMID38932367
PMCPMC11209438

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.