Evidence map›Paper›PMID 38932366›Full record

ArticleVaccines2024

Immuno-Microbial Signature of Vaccine-Induced Immunity against SARS-CoV-2.

Lesley Umeda, Amada Torres, Braden P Kunihiro, Noelle C Rubas, Riley K Wells, Krit Phankitnirundorn, Rafael Peres, Ruben Juarez, Alika K Maunakea

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lesley UmedaDepartment of Molecular Biosciences and Bioengineering, University of Hawaii, Honolulu, HI 96822, USA.
Amada TorresDepartment of Anatomy, Biochemistry, and Physiology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96822, USA.ORCID 0000-0001-7010-1294
Braden P KunihiroDepartment of Molecular Biosciences and Bioengineering, University of Hawaii, Honolulu, HI 96822, USA.
Noelle C RubasDepartment of Molecular Biosciences and Bioengineering, University of Hawaii, Honolulu, HI 96822, USA.
Riley K WellsDepartment of Molecular Biosciences and Bioengineering, University of Hawaii, Honolulu, HI 96822, USA.ORCID 0009-0005-3263-8230
Krit PhankitnirundornDepartment of Anatomy, Biochemistry, and Physiology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96822, USA.ORCID 0000-0002-8022-202X
Rafael PeresDepartment of Anatomy, Biochemistry, and Physiology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96822, USA.
Ruben JuarezDepartment of Economics and UHERO, University of Hawaii, Honolulu, HI 96822, USA.ORCID 0000-0001-8179-6001
Alika K MaunakeaDepartment of Anatomy, Biochemistry, and Physiology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96822, USA.ORCID 0000-0002-6457-5087

Funding

The Role of gp120 on Cardiovascular Disease in People Living with HIVU54MD007601 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI Kathryn Lenzner Braun · 2017 to 2026
$59.5M
Empowering schools as community assets to mitigate the adverse impacts of COVID-19OT2HD108105 · NICHD · UNIVERSITY OF HAWAII AT MANOA · PI JUAREZ, RUBEN, MAUNAKEA, ALIKA KEOLAOKALANI · 2021 to 2022
$3.8M
Socioecological Determinants of Immunoepigenetic Signatures of Diabetes Risk in Indigenous CommunitiesR01MD016593 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI MAUNAKEA, ALIKA KEOLAOKALANI · 2021 to 2025
$3.3M
Immunoepigenetic-gut microbiome axis in the social networks of health disparate youthR56MD014630 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI MAUNAKEA, ALIKA KEOLAOKALANI · 2019 to 2019
$386k
Army Grant W911NF21P0025Hawaii Community Foundation 20HCF-101573NICHD NIH HHS OT2 HD108105NIMHD NIH HHS R01 MD016593NIMHD NIH HHS R56 MD014630NIMHD NIH HHS U54 MD007601
6 · The paper itself

Abstract

Although vaccines address critical public health needs, inter-individual differences in responses are not always considered in their development. Understanding the underlying basis for these differences is needed to optimize vaccine effectiveness and ultimately improve disease control. In this pilot study, pre- and post-antiviral immunological and gut microbiota features were characterized to examine inter-individual differences in SARS-CoV-2 mRNA vaccine response. Blood and stool samples were collected before administration of the vaccine and at 2-to-4-week intervals after the first dose. A cohort of 14 adults was separated

Indexed as

gut microbiomeHMGB-1inflammationSARS-CoV-2vaccine

Identifiers

PMID38932366
PMCPMC11209251

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.