Evidence map›Paper›PMID 38932317›Full record

ArticleVaccines2024

A Nasal Vaccine Candidate, Containing Three Antigenic Regions from SARS-CoV-2, to Induce a Broader Response.

Yadira Lobaina, Rong Chen, Edith Suzarte, Panchao Ai, Alexis Musacchio, Yaqin Lan, Glay Chinea, Changyuan Tan, Ricardo Silva, Gerardo Guillen and 4 more

Abstract read
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yadira LobainaResearch Department, China-Cuba Biotechnology Joint Innovation Center (CCBJIC), Lengshuitan District, Yongzhou 425000, China.
Rong ChenResearch Department, China-Cuba Biotechnology Joint Innovation Center (CCBJIC), Lengshuitan District, Yongzhou 425000, China.
Edith SuzarteResearch Department, Center for Genetic Engineering and Biotechnology, Havana 10600, Cuba.
Panchao AiResearch Department, China-Cuba Biotechnology Joint Innovation Center (CCBJIC), Lengshuitan District, Yongzhou 425000, China.
Alexis MusacchioResearch Department, China-Cuba Biotechnology Joint Innovation Center (CCBJIC), Lengshuitan District, Yongzhou 425000, China.
Yaqin LanResearch Department, China-Cuba Biotechnology Joint Innovation Center (CCBJIC), Lengshuitan District, Yongzhou 425000, China.ORCID 0000-0002-4397-7765
Glay ChineaResearch Department, Center for Genetic Engineering and Biotechnology, Havana 10600, Cuba.
Changyuan TanResearch Department, China-Cuba Biotechnology Joint Innovation Center (CCBJIC), Lengshuitan District, Yongzhou 425000, China.ORCID 0000-0002-0803-3339
Ricardo SilvaScience and Innovation Directorate, BioCubaFarma, Independence Avenue, No. 8126, Corner 100 Street, Havana 10800, Cuba.
Gerardo GuillenResearch Department, Center for Genetic Engineering and Biotechnology, Havana 10600, Cuba.ORCID 0000-0003-3098-0970
Ke YangResearch Department, China-Cuba Biotechnology Joint Innovation Center (CCBJIC), Lengshuitan District, Yongzhou 425000, China.ORCID 0000-0001-8527-8930
Wen LiResearch Department, China-Cuba Biotechnology Joint Innovation Center (CCBJIC), Lengshuitan District, Yongzhou 425000, China.
Yasser PereraResearch Department, China-Cuba Biotechnology Joint Innovation Center (CCBJIC), Lengshuitan District, Yongzhou 425000, China.
Lisset HermidaResearch Department, China-Cuba Biotechnology Joint Innovation Center (CCBJIC), Lengshuitan District, Yongzhou 425000, China.

Funding

Hunan Provincial Base for Scientific and Technological Innovation Cooperation 2019CB1012Hunan Provincial Innovative Construction Program 2020WK2031MOST "National key R&D program of China" 2021YFE0192200PNCT CITMA, CubaThe Science and Technology Innovation Program of Hunan Province 2020RC5035
6 · The paper itself

Abstract

A chimeric protein, formed by two fragments of the conserved nucleocapsid (N) and S2 proteins from SARS-CoV-2, was obtained as a recombinant construct in

Indexed as

chimeric proteinintranasal vaccinenucleocapsidRBDS2 fibreSARS-CoV-2

Identifiers

PMID38932317
PMCPMC11209543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.